A6ZI44 (A6ZI44_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Fructose-bisphosphate aldolase RuleBase RU003994
EC=4.1.2.13 RuleBase RU003994

Gene names

Name:	Aldoa MGI 87994 EMBL ABR58859.1 Ensembl ENSMUSP00000084846
ORF Names:	mCG_22383 EMBL EDL17445.1

Organism

Mus musculus (Mouse) EMBL ABR58859.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	418 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. RuleBase RU003994
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4. RuleBase RU004257
Sequence similarities	Belongs to the class I fructose-bisphosphate aldolase family. RuleBase RU003994

Ontologies

Keywords
Biological process	Glycolysis RuleBase RU003994
Molecular function	Lyase RuleBase RU003994
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	flagellum Inferred from direct assay. Source: MGI
Molecular function	fructose-bisphosphate aldolase activity Inferred from direct assay. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6ZI44 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 945DC1228901AF1C	FASTA	418	45,120
	10 20 30 40 50 60 MATRRPDGSS FNMTRLSLAL AFSFPPVASE QPHSELGNTQ QQTELGKEST ATGTMPHPYP 70 80 90 100 110 120 ALTPEQKKEL SDIAHRIVAP GKGILAADES TGSIAKRLQS IGTENTEENR RFYRQLLLTA 130 140 150 160 170 180 DDRVNPCIGG VILFHETLYQ KADDGRPFPQ VIKSKGGVVG IKVDKGVVPL AGTNGETTTQ 190 200 210 220 230 240 GLDGLSERCA QYKKDGADFA KWRCVLKIGE HTPSALAIME NANVLARYAS ICQQNGIVPI 250 260 270 280 290 300 VEPEILPDGD HDLKRCQYVT EKVLAAVYKA LSDHHVYLEG TLLKPNMVTP GHACTQKFSN 310 320 330 340 350 360 EEIAMATVTA LRRTVPPAVT GVTFLSGGQS EEEASINLNA INKCPLLKPW ALTFSYGRAL 370 380 390 400 410 QASALKAWGG KKENLKAAQE EYIKRALANS LACQGKYTPS GQSGAAASES LFISNHAY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Three male germline-specific aldolase A isozymes are generated by alternative splicing and retrotransposition." Vemuganti S.A., Bell T.A., Scarlett C.O., Parker C.E., Pardo-Manuel de Villena F., O'Brien D.A. Dev. Biol. 309:18-31(2007) [PubMed: 17659271] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: CD1 EMBL ABR58859.1. Tissue: Testis EMBL ABR58859.1.
[2]	"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D. Science 296:1661-1671(2002) [PubMed: 12040188] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL17445.1.
[3]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Mouse Genome Sequencing Consortium Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6 Ensembl ENSMUSP00000084846.
[4]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000084846.
[5]	Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL17445.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC124505 Genomic DNA. No translation available. EF662059 mRNA. Translation: ABR58859.1. CH466531 Genomic DNA. Translation: EDL17445.1.
IPI	IPI00856379.
RefSeq	NP_001170778.1. NM_001177307.1.
UniGene	Mm.275831.
3D structure databases
ProteinModelPortal	A6ZI44.
SMR	A6ZI44. Positions 59-398.
ModBase	Search...
Protein-protein interaction databases
IntAct	A6ZI44. 1 interaction.
STRING	A6ZI44.
Proteomic databases
PRIDE	A6ZI44.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000087566; ENSMUSP00000084846; ENSMUSG00000030695.
GeneID	11674.
KEGG	mmu:11674.
Organism-specific databases
CTD	226.
MGI	MGI:87994. Aldoa.
Phylogenomic databases
HOVERGEN	HBG002386.
InParanoid	A6ZI44.
OMA	REMLFRS.
Gene expression databases
Bgee	A6ZI44.
Genevestigator	A6ZI44.
Family and domain databases
InterPro	IPR000741. Aldolase_I. IPR013785. Aldolase_TIM. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01623.
PANTHER	PTHR11627. Aldolase_I. 1 hit.
Pfam	PF00274. Glycolytic. 1 hit. [Graphical view]
PROSITE	PS00158. ALDOLASE_CLASS_I. 1 hit. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

A6ZI44_MOUSE

Accession

Primary (citable) accession number: A6ZI44

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	November 16, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)