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A6YVI1 (A6YVI1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome b RuleBase RU000300
Gene names
Name:CYTB EMBL ABR93711.1
Encoded onMitochondrion EMBL ABR93711.1
OrganismHomo sapiens (Human) EMBL ABR93711.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length378 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis By similarity. RuleBase RU000300

Cofactor

Binds 2 heme groups non-covalently By similarity. RuleBase RU000300

Sequence similarities

Belongs to the cytochrome b family. RuleBase RU000300

Sequences

Sequence LengthMass (Da)Tools
A6YVI1 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 720C262E54980879

FASTA37842,460
        10         20         30         40         50         60 
MTPMRKTNPL MKLINHSFID LPTPSNISAW WNFGSLLGAC LILQITTGLF LAMHYSPDAS 

        70         80         90        100        110        120 
TAFSSIAHIT RDVNYGWIIR YLHANGASMF FICLFLHIGR GLYYGSFLYS ETWNIGIILL 

       130        140        150        160        170        180 
LATMATAFMG YVLPWGQMSF WGATVITNLL SAIPYIGTDL VQWIWGGYSV DSPTLTRFFT 

       190        200        210        220        230        240 
FHFILPFIIA ALATLHLLFL HETGSNNPLG ITSHSDKITF HPYYTIKDAL GLLLFLLSLM 

       250        260        270        280        290        300 
TLTLFSPDLL GDPDNYTLAN PLNTPPHIKP EWYFLFAYTI LRSVPNKLGG VLALLLSILI 

       310        320        330        340        350        360 
LAMIPILHMS KQQSMMFRPL SQSLYWLLAA DLLILTWIGG QPVSYPFTII GQVASVLYFT 

       370 
TILILMPTIS LIENKMLK 

« Hide

References

[1]"Reduced-median-network analysis of complete mitochondrial DNA coding-region sequences for the major African, Asian, and European haplogroups."
Herrnstadt C., Elson J.L., Fahy E., Preston G., Turnbull D.M., Anderson C., Ghosh S.S., Olefsky J.M., Beal M.F., Davis R.E., Howell N.
Am. J. Hum. Genet. 70:1152-1171(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MTDNA15 EMBL ABR93711.1, MTDNA286 EMBL ABR95669.1, MTDNA341 EMBL ABR96473.1, MTDNA412 EMBL ABR97498.1, MTDNA475 EMBL ABR98394.1, MTDNA525 EMBL ABR99121.1 and MTDNA526 EMBL ABR99134.1.
[2]Herrnstadt C., Fahy E., Preston G., Anderson C., Ghosh S.S., Davis R.E., Howell N.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MTDNA15 EMBL ABR93711.1, MTDNA286 EMBL ABR95669.1, MTDNA341 EMBL ABR96473.1, MTDNA412 EMBL ABR97498.1, MTDNA475 EMBL ABR98394.1, MTDNA525 EMBL ABR99121.1 and MTDNA526 EMBL ABR99134.1.
[3]HmtDB
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MTDNA15 EMBL ABR93711.1, MTDNA286 EMBL ABR95669.1, MTDNA341 EMBL ABR96473.1, MTDNA412 EMBL ABR97498.1, MTDNA475 EMBL ABR98394.1, MTDNA525 EMBL ABR99121.1 and MTDNA526 EMBL ABR99134.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EF657287 Genomic DNA. Translation: ABR93711.1.
EF657438 Genomic DNA. Translation: ABR95669.1.
EF657500 Genomic DNA. Translation: ABR96473.1.
EF657579 Genomic DNA. Translation: ABR97498.1.
EF657648 Genomic DNA. Translation: ABR98394.1.
EF657704 Genomic DNA. Translation: ABR99121.1.
EF657705 Genomic DNA. Translation: ABR99134.1.

3D structure databases

ProteinModelPortalA6YVI1.
SMRA6YVI1. Positions 1-378.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG017694.

Gene expression databases

BgeeA6YVI1.

Family and domain databases

Gene3D1.20.810.10. 1 hit.
InterProIPR016175. Cyt_b/b6.
IPR005798. Cyt_b/b6_C.
IPR005797. Cyt_b/b6_N.
IPR027387. Cytb/b6-like.
IPR016174. Di-haem_cyt_TM.
[Graphical view]
PANTHERPTHR19271:SF0. PTHR19271:SF0. 1 hit.
PfamPF00032. Cytochrom_B_C. 1 hit.
PF13631. Cytochrom_B_N_2. 1 hit.
[Graphical view]
SUPFAMSSF81342. SSF81342. 1 hit.
SSF81648. SSF81648. 1 hit.
PROSITEPS51003. CYTB_CTER. 1 hit.
PS51002. CYTB_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35462946.

Entry information

Entry nameA6YVI1_HUMAN
AccessionPrimary (citable) accession number: A6YVI1
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: April 16, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.