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Protein
Submitted name:

Sterol regulatory element binding transcription factor 1

Gene

srebf1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Sterol regulatory element binding transcription factor 1Imported
Gene namesi
Name:srebf1Imported
Synonyms:SREBF1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-090812-3. srebf1.

Structurei

3D structure databases

ProteinModelPortaliA6XLD8.
SMRiA6XLD8. Positions 315-394.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini317 – 36751BHLH (basic helix-loop-helix)InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili357 – 39135Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains 1 basic helix-loop-helix (bHLH) domain.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000007091.
HOVERGENiHBG061592.
KOiK07197.
PhylomeDBiA6XLD8.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
[Graphical view]
PfamiPF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6XLD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLSFDDTSL DTLDSSLSLH DPSDIDTALL NDIDDMLQLI NTQDMEFGLF
60 70 80 90 100
DQASFPAPAA PAQEQLHSSP ASPAAAPPPA ASSILSSSPH LDALLGPPIT
110 120 130 140 150
RSSSIPTDKA FQPHTFQQAP LAQVNSTPAA LQTTQPKAQP APSASLQPSS
160 170 180 190 200
QTPPSASSSP QQTLYSSYTT HTTYTPVTQQ SSPQSIPSLS ASPQNIQPMT
210 220 230 240 250
IQSVSASPIL TASSSPPTQP LPPQVQQLPV LLQPQFIKAD SLLLTTLKPD
260 270 280 290 300
VTMVTTVASP CITTLTSTAP VQNTPLQALM SGGTILTTVP LVVDTEKLPI
310 320 330 340 350
NRIAISGKPG CQPHKGEKRT AHNAIEKRYR SSINDKIIEL KDLVAGTEAK
360 370 380 390 400
LNKSAVLKKA IEYIRYLQQS NQKLKQENMA LKMNIQKNKS LKDLVTMEVD
410 420 430 440 450
VKPEIPTPPA SDVGSPQSSG PYSQHSSDSE PDSPMAEDSK AVVERAGGML
460 470 480 490 500
DRSRMALCAF TLLFLSFNPL ASLLCGGWSS AGASVPGNAA GRSVLSLEDS
510 520 530 540 550
GESWGWMDWM LPTLLVWLLN GVLVAGVLIR LQVYGEPMTR PHSESSVLFW
560 570 580 590 600
GHRKPADLDL ARGDFAQASQ NLRTCLKALG RPLPPSQLDL ACAVLWSALR
610 620 630 640 650
LCLQRLWVGR WLASRAGALR PNRPLQEDNC KSCRDAALVY HRLHQLHMTG
660 670 680 690 700
KLGGSHLSAI HMALSALNLA ECAGDCLPVA TLAEVYVSAA LRVKTSLPRL
710 720 730 740 750
LHFTTRVFLS SARQACLSPS GSVPPAMQWL CHPLGHRFFV DEDWTIRSSP
760 770 780 790 800
RESIYSQAGN SVDPLAQVTQ GFREHLLEKA LYCVAQPRGD KSLADGDGEF
810 820 830 840 850
SDALEYLQLL TSAADAAGAT TQSFAIGSNM ATVTGCDPHS KWWSSMVVVV
860 870 880 890 900
TNWLQGEDAA AERLYPAVEH LPRSLQSAES PLPKACVNVF KAVRTLLAKP
910 920 930 940 950
ESQQPSLSYC ERASVLFRDS LNLGPHCSAS TQLDKLVQLL LCDLLLVTRT
960 970 980 990 1000
NVWRDQQVCS SSSTAAASPA ELQGFQQDLS SLRRLAHSFR PATRRLFLHE
1010 1020 1030 1040 1050
ATARLMAGAS PTRTHQLLDR SLRRRATPGA RIEECELHPG QREQAEAVML
1060 1070 1080 1090 1100
ACRFLPPSFL SAPGQRVGML ADAARTLEKL GDKRTLHDCQ QMIIKLGSGT

TVTST
Length:1,105
Mass (Da):119,316
Last modified:August 21, 2007 - v1
Checksum:i7FDBF605AA4F8CA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ836065 mRNA. Translation: ABI33876.1.
RefSeqiNP_001098599.1. NM_001105129.1.
UniGeneiDr.78402.

Genome annotation databases

GeneIDi793274.
KEGGidre:793274.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ836065 mRNA. Translation: ABI33876.1.
RefSeqiNP_001098599.1. NM_001105129.1.
UniGeneiDr.78402.

3D structure databases

ProteinModelPortaliA6XLD8.
SMRiA6XLD8. Positions 315-394.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi793274.
KEGGidre:793274.

Organism-specific databases

CTDi6720.
ZFINiZDB-GENE-090812-3. srebf1.

Phylogenomic databases

HOGENOMiHOG000007091.
HOVERGENiHBG061592.
KOiK07197.
PhylomeDBiA6XLD8.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
[Graphical view]
PfamiPF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA6XLD8_DANRE
AccessioniPrimary (citable) accession number: A6XLD8
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: June 8, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.