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Unreviewed, UniProtKB/TrEMBL A6XGL2 (A6XGL2_HUMAN)

Last modified February 9, 2010. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Insulin EMBL ABI63346.1
Submitted name:
    Putative uncharacterized protein INS Ensembl ENSP00000370720
Gene names
Name: INS Ensembl ENSP00000370720
OrganismHomo sapiens (Human) EMBL ABI63346.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length98 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Subcellular location

Secreted By similarity RuleBase RU000406V1.

Sequence similarities

Belongs to the insulin family.

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Ontologies

Gene Ontology (GO)
   Cellular componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionhormone activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequences

Sequence LengthMass (Da)Tools
A6XGL2-1 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 6DDEDC02ED1A9CB9

FASTA9810,959
        10         20         30         40         50         60 
MALWMRLLPL LALLALWGPD PAAAFVNQHL CGSHLVEALY LVCGERGFFY TPKTRREAED 

        70         80         90 
LQGSLQPLAL EGSLQKRGIV EQCCTSICSL YQLENYCN

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References

« Hide 'large scale' references
[1]"A computer system platform used to predict novel genes."
Yu Z., Zheng Z., Tang T., Fu Y.
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[2]Ensembl
Submitted (OCT-2009) to UniProtKB
Cited for: IDENTIFICATION.
[3]"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. expand/collapse author list , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y.
Nature 440:497-500(2006) [PubMed: 16554811] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC132217 Genomic DNA. No translation available.
DQ778082 mRNA. Translation: ABI63346.1.
IPIIPI00853225.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2W44X-ray2.00A/C/E82-98[»]
B/D/F25-53[»]
SMRA6XGL2. Positions 25-98.
ModBaseSearch...

Genome annotation databases

EnsemblENST00000381319; ENSP00000370720; ENSG00000129965; Homo sapiens. [Genome view]
UCSCuc009ydg.1. human.

Organism-specific databases

HGNCHGNC:6081. INS.
GenAtlasSearch...

Gene expression databases

BgeeA6XGL2.

Family and domain databases

InterProIPR004825. Ins/IGF/relaxin.
IPR016179. Insulin-like.
[Graphical view]
Gene3DG3DSA:1.10.100.10. Ins/IGF/relaxin. 1 hit.
PfamPF00049. Insulin. 1 hit.
[Graphical view]
PRINTSPR00277. INSULINB.
SMARTSM00078. IlGF. 1 hit.
[Graphical view]
PROSITEPS00262. INSULIN. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameA6XGL2_HUMAN
AccessionPrimary (citable) accession number: A6XGL2
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: February 9, 2010
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information