A6X798 (3HAO_OCHA4) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 32.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: 3-hydroxyanthranilate 3,4-dioxygenase EC=1.13.11.6 Alternative name(s): 3-hydroxyanthranilate oxygenase Short name=3-HAO 3-hydroxyanthranilic acid dioxygenase Short name=HAD | ||
| Gene names |
| ||
| Organism | Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168) [Complete proteome] [HAMAP] | ||
| Taxonomic identifier | 439375 [NCBI] | ||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Ochrobactrum |
Protein attributes
| Sequence length | 182 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate By similarity. HAMAP MF_00825 |
| Catalytic activity | 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde. HAMAP MF_00825 |
| Cofactor | Binds 2 Fe2+ ions per subunit By similarity. HAMAP MF_00825 |
| Subunit structure | Homodimer By similarity. HAMAP MF_00825 |
| Sequence similarities | Belongs to the 3-HAO family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | Iron Metal-binding |
| Molecular function | Dioxygenase Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Molecular function | 3-hydroxyanthranilate 3,4-dioxygenase activity Inferred from electronic annotation. Source: EC iron ion bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 182 | 182 | 3-hydroxyanthranilate 3,4-dioxygenase HAMAP MF_00825 | PRO_0000309576 | |||||
Sites | |||||||||
| Metal binding | 50 | 1 | Iron 1; catalytic By similarity | ||||||
| Metal binding | 56 | 1 | Iron 1; catalytic By similarity | ||||||
| Metal binding | 96 | 1 | Iron 1; catalytic By similarity | ||||||
| Metal binding | 126 | 1 | Iron 2 By similarity | ||||||
| Metal binding | 129 | 1 | Iron 2 By similarity | ||||||
| Metal binding | 163 | 1 | Iron 2 By similarity | ||||||
| Metal binding | 166 | 1 | Iron 2 By similarity | ||||||
| Binding site | 46 | 1 | Dioxygen By similarity | ||||||
| Binding site | 56 | 1 | Substrate By similarity | ||||||
| Binding site | 100 | 1 | Substrate By similarity | ||||||
| Binding site | 111 | 1 | Substrate By similarity | ||||||
Sequences
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References
| [1] | "Complete sequence of chromosome 2 of Ochrobactrum anthropi ATCC 49188." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Garcia E., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49188 / DSM 6882 / NCTC 12168. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000759 Genomic DNA. Translation: ABS17102.1. |
| RefSeq | YP_001372931.1. NC_009668.1. |
3D structure databases | |
| ProteinModelPortal | A6X798. |
| SMR | A6X798. Positions 1-173. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A6X798. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 5382663. |
| GenomeReviews | Gene locus Oant_4402 in contig CP000759_GR. |
| KEGG | oan:Oant_4402. |
| PATRIC | 20474238. VBIOchAnt73124_4578. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | NOG77058. |
| HOGENOM | HBG341987. |
| OMA | LKPPVNN. |
| ProtClustDB | PRK13264. |
Enzyme and pathway databases | |
| BioCyc | OANT439375:OANT_4402-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00825. 3_HAO. [Tree] |
| InterPro | IPR010329. 3hydroanth_dOase. IPR011051. Cupin_RmlC_type. IPR014710. RmlC-like_jellyroll. [Graphical view] |
| Gene3D | G3DSA:2.60.120.10. RmlC-like_jellyroll. 1 hit. |
| KO | K00452. |
| PANTHER | PTHR15497. PTHR15497. 1 hit. |
| Pfam | PF06052. 3-HAO. 1 hit. [Graphical view] |
| SUPFAM | SSF51182. RmlC_like_cupin. 1 hit. |
| TIGRFAMs | TIGR03037. Anthran_nbaC. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | 3HAO_OCHA4 | ||||||||
| Accession | Primary (citable) accession number: A6X798 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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