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Reviewed, UniProtKB/Swiss-Prot A6X792 (ASPD_OCHA4)

Last modified November 3, 2009. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable L-aspartate dehydrogenase
    EC=1.4.1.21
Gene names
Name: nadX
Ordered Locus Names: Oant_4396
OrganismOchrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168) [Complete proteome] [HAMAP]
Taxonomic identifier439375 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeOchrobactrum

Protein attributes

Sequence length268 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity.

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity.

Sequence similarities

Belongs to the L-aspartate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 268268Probable L-aspartate dehydrogenase HAMAP MF_01265
PRO_1000067309

Sites

Active site2211 By similarity
Binding site1251NAD; via amide nitrogen By similarity
Binding site1911NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
A6X792-1 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 32BA43AEF0CCFC12

FASTA26827,854
        10         20         30         40         50         60 
MSVSETIVLV GWGAIGKRVA DLLAERKSSV RIGAVAVRDR SASRDRLPAG AVLIENPAEL 

        70         80         90        100        110        120 
AASGASLVVE AAGRPSVLPW GEAALSTGMD FAVSSTSAFV DDALFQRLKD AAAASGAKLI 

       130        140        150        160        170        180 
IPPGALGGID ALSAASRLSI ESVEHRIIKP AKAWAGTQAA QLVPLDEISE ATVFFTDTAR 

       190        200        210        220        230        240 
KAADAFPQNA NVAVITSLAG IGLDRTRVTL VADPAARLNT HEIIAEGDFG RMHLRFENGP 

       250        260 
LATNPKSSEM TALNLVRAIE NRVATTVI 

« Hide

References

[1]"Complete sequence of chromosome 2 of Ochrobactrum anthropi ATCC 49188."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Garcia E., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000759 Genomic DNA. Translation: ABS17096.1.
RefSeqYP_001372925.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA6X792.

Genome annotation databases

GeneID5381939.
GenomeReviewsGene locus Oant_4396 in contig CP000759_GR.
KEGGoan:Oant_4396.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAECAGHSA.

Family and domain databases

HAMAPMF_01265.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
[Graphical view]
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProDomPD017325. Asp_dh. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameASPD_OCHA4
AccessionPrimary (citable) accession number: A6X792
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 21, 2007
Last modified: November 3, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents