A6X3Q1 (A6X3Q1_OCHA4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase 2 HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2-2 HAMAP MF_01902
Ordered Locus Names:	Oant_3147

Organism

Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168) [Complete proteome] [HAMAP] EMBL ABS15855.1

Taxonomic identifier

439375 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Ochrobactrum

Protein attributes

Sequence length	1059 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6X3Q1 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 77F564CAE3D00367	FASTA	1,059	118,393
	10 20 30 40 50 60 MSAPAYAELQ VTSHFSFLRG ASSAEELFAA AAAMGIEALA VTDRNTLAGI VRAHEAAKEA 70 80 90 100 110 120 GVRLIVGCRL DLACGMSVLV YPTDRAAYSR LCRLLSLGKG RAGKARCHLE WDDLVAYGEG 130 140 150 160 170 180 LIVVLAPDLA DETCGLRLRR LRDAFGDRAY LGLTLRRRPN DQMRLWELST LAAGLGVPTV 190 200 210 220 230 240 VTNDVLFHEP GRRILQDVVT AIRHNLTVDA LGTRRDRHAD RYLKPPAEMH RLFARWPEAL 250 260 270 280 290 300 ARTREIADRC RFSLDELRYQ YPEERDDPAL TPQETLERLT WEGAASRYPE GVPDEVTAAL 310 320 330 340 350 360 KHELALIGKL DYAPYFLTVN SIVRFARSRG ILCQGRGSAA NSAVCYVLGI TAIDPGRNDL 370 380 390 400 410 420 LFERFVSEER REPPDIDVDF EHERREEVIQ WVYEHYGRER AALTATVIRY RSKGALRDVG 430 440 450 460 470 480 KALGLPEDLI QTLSGQLWGW SEAGVTEQQL RDLNLNPQDR RLRLTLELAA QLRGAPRHLS 490 500 510 520 530 540 QHPGGFVLTH DRLDDLVPIE PAAMEGRQII EWDKDDIDAL RFMKVDVLAL GMLSCMRRGL 550 560 570 580 590 600 DLLAEHKDIR LDLASIPAED PRTYAMIRKA DTLGTFQIES RAQMSMLPRL KPRTYYDLVV 610 620 630 640 650 660 QVAIVRPGPI QGDMVHPYLR RREGLEEVDY PRPELEKVLG KTLGVPLFQE QAMRVAIECA 670 680 690 700 710 720 GFTAGEADLL RKSMATFKHT GGVSKFRDRL ISGMIERGYE QDFAERTFQQ LEGFGSYGFP 730 740 750 760 770 780 ESHAASFALI AYASAWLKCW HPDVFCAALL NAQPMGFYAP AQIVRDAREH EVEVRPVCIN 790 800 810 820 830 840 ASRWDCTLEP TGDESRFAVR LGLRMVKGLA NAHAAAIVAA QGDEMFTSVD DLWRRAGVPV 850 860 870 880 890 900 AALDQIAAAD GFRPAFGLAR REAQWAIKGL RDEELPLFAA ASEREGRTVP ELDEPAIALR 910 920 930 940 950 960 AMPAGREVVE DYGHIGLSLR RHPVSFLRED LARRRIVTCA EAMAARDQRW LEAAGIVLVR 970 980 990 1000 1010 1020 QRPGSANGVM FITLEDETGI ANLVVWQKIF ERYRRVILSS SMIAVRGRVQ REGEVVHLVA 1030 1040 1050 HRIVDLSRDL ATVVQREVAT DGQQGPGAGG IRVKARDFR

References

[1]

"Complete sequence of chromosome 2 of Ochrobactrum anthropi ATCC 49188." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Garcia E., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000759 Genomic DNA. Translation: ABS15855.1.
RefSeq	YP_001371684.1. NC_009668.1.
3D structure databases
ProteinModelPortal	A6X3Q1.
ModBase	Search...
Protein-protein interaction databases
STRING	A6X3Q1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5382884.
GenomeReviews	Gene locus Oant_3147 in contig CP000759_GR.
KEGG	oan:Oant_3147.
PATRIC	20471648. VBIOchAnt73124_3297.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	ADYCANG.
ProtClustDB	CLSK881842.
Enzyme and pathway databases
BioCyc	OANT439375:OANT_3147-MONOMER.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6X3Q1_OCHA4

Accession

Primary (citable) accession number: A6X3Q1

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)