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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / JCM 21032 / NBRC 15819 / NCTC 12168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciOANT439375:GJIT-3049-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:Oant_2996
OrganismiOchrobactrum anthropi (strain ATCC 49188 / DSM 6882 / JCM 21032 / NBRC 15819 / NCTC 12168)
Taxonomic identifieri439375 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeOchrobactrum
Proteomesi
  • UP000002301 Componenti: Chromosome 2

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 527527Exodeoxyribonuclease 7 large subunitPRO_1000048778Add
BLAST

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Protein-protein interaction databases

STRINGi439375.Oant_2996.

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229266.
KOiK03601.
OMAiPFMPKVI.
OrthoDBiPOG091H02EK.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

A6X3A0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSDSSFTGA SSNVAEYSVS EISGALKRTV EDTFGHVRVR GEISGYRGPH
60 70 80 90 100
SSGHAYFALK DDRARLEAVI WRGSMSRLRF RPEEGMEVIA TGKLTTYPGS
110 120 130 140 150
SKYQIVIEQM EPAGAGALMA LLEERKRRLA TEGLFDPAVK QLLPFMPRVI
160 170 180 190 200
GVVTSPTGAV IRDIIHRIAD RYPLHVIVWP VRVQGETSGP EVAAAVDGFN
210 220 230 240 250
ALPDEGNIPR PDVLIVARGG GSLEDLWGFN DEIVVRAVAA SHIPVISAVG
260 270 280 290 300
HETDWTLIDL AADIRAPTPT GAAEMAVPVK ADLLATLAGQ SARLSSAMSR
310 320 330 340 350
FIDLKRQAHR SAARALPSAD QLLALPRRRF DEAAARLTRA LFVNTQKKRV
360 370 380 390 400
HFDGHARQLS PRLLQRRFTE LQRDVSALGQ RLPRALEAFL RERRTAFIHR
410 420 430 440 450
ANRLSAEPIL RRTKLTSVAI EQLDRRRDQA VRLLIERAKR RGQELERLMR
460 470 480 490 500
TLSYESVLER GFAVVFDEEG KPVKQAGSVS AGDALSIRFR DGEVAVVAGD
510 520
EDESEPAKLV QTKKVQSPGS GNQGSLF
Length:527
Mass (Da):57,887
Last modified:August 21, 2007 - v1
Checksum:iE1D4F990E799BFEA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000759 Genomic DNA. Translation: ABS15704.1.
RefSeqiWP_011982723.1. NC_009668.1.

Genome annotation databases

EnsemblBacteriaiABS15704; ABS15704; Oant_2996.
GeneIDi5382935.
KEGGioan:Oant_2996.
PATRICi20471336. VBIOchAnt73124_3147.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000759 Genomic DNA. Translation: ABS15704.1.
RefSeqiWP_011982723.1. NC_009668.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi439375.Oant_2996.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABS15704; ABS15704; Oant_2996.
GeneIDi5382935.
KEGGioan:Oant_2996.
PATRICi20471336. VBIOchAnt73124_3147.

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229266.
KOiK03601.
OMAiPFMPKVI.
OrthoDBiPOG091H02EK.

Enzyme and pathway databases

BioCyciOANT439375:GJIT-3049-MONOMER.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiEX7L_OCHA4
AccessioniPrimary (citable) accession number: A6X3A0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: September 7, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.