A6X0A2 (EFTU_OCHA4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Elongation factor Tu
Short name=EF-Tu

Gene names

Name:	tuf1
Ordered Locus Names:	Oant_1940
AND
Name:	tuf2
Ordered Locus Names:	Oant_1954

Organism

Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168) [Complete proteome] [HAMAP]

Taxonomic identifier

439375 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Ochrobactrum › Ochrobactrum anthropi

Protein attributes

Sequence length	391 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	GTP-binding Nucleotide-binding
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 391	391	Elongation factor Tu HAMAP-Rule MF_00118		PRO_0000337449
Regions
	Nucleotide binding	19 – 26	8	GTP By similarity
	Nucleotide binding	76 – 80	5	GTP By similarity
	Nucleotide binding	131 – 134	4	GTP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A6X0A2 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 3C414FE14FBFC54B	FASTA	391	42,574
	10 20 30 40 50 60 MAKSKFERTK PHVNIGTIGH VDHGKTSLTA AITKFFGEFK AYDQIDAAPE ERARGITIST 70 80 90 100 110 120 AHVEYETPNR HYAHVDCPGH ADYVKNMITG AAQMDGAILV VSAADGPMPQ TREHILLARQ 130 140 150 160 170 180 VGVPAIVVFL NKCDQVDDAE LLELVELEVR ELLSKYDFPG DEVPIIKGSA LAALEDSSKE 190 200 210 220 230 240 LGEDAVRSLM AAVDDYIPTP ERPIDQPFLM PIEDVFSISG RGTVVTGRVE RGIVKVGEEV 250 260 270 280 290 300 EIVGIKATAK TTVTGVEMFR KLLDQGQAGD NIGALIRGVG REDVERGQVL CKPGSVKPHT 310 320 330 340 350 360 KFKAEAYILT KDEGGRHTPF FTNYRPQFYF RTTDVTGVVT LPEGTEMVMP GDNVAMDVTL 370 380 390 IVPIAMEEKL RFAIREGGRT VGAGIVSSII E

References

[1]

"Genome of Ochrobactrum anthropi ATCC 49188 T, a versatile opportunistic pathogen and symbiont of several eukaryotic hosts." Chain P.S., Lang D.M., Comerci D.J., Malfatti S.A., Vergez L.M., Shin M., Ugalde R.A., Garcia E., Tolmasky M.E. J. Bacteriol. 193:4274-4275(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49188 / DSM 6882 / NCTC 12168.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000758 Genomic DNA. Translation: ABS14656.1. CP000758 Genomic DNA. Translation: ABS14670.1.
RefSeq	YP_001370485.1. NC_009667.1. YP_001370499.1. NC_009667.1.
3D structure databases
ProteinModelPortal	A6X0A2.
SMR	A6X0A2. Positions 2-390.
ModBase	Search...
Protein-protein interaction databases
STRING	439375.Oant_1954.
Proteomic databases
PRIDE	A6X0A2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABS14656; ABS14656; Oant_1940. ABS14670; ABS14670; Oant_1954.
GeneID	5378469. 5381162.
KEGG	oan:Oant_1940. oan:Oant_1954.
PATRIC	20469091. VBIOchAnt73124_2043.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0050.
HOGENOM	HOG000229290.
KO	K02358.
OMA	ANQMECA.
ProtClustDB	PRK12735.
Enzyme and pathway databases
BioCyc	OANT439375:GJIT-1975-MONOMER. OANT439375:GJIT-1990-MONOMER.
Family and domain databases
HAMAP	MF_00118_B. EF_Tu_B.
InterPro	IPR000795. EF_GTP-bd_dom. IPR005225. Small_GTP-bd_dom. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFTU_OCHA4

Accession

Primary (citable) accession number: A6X0A2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	August 21, 2007
Last modified:	May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program