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Protein

Trans-aconitate 2-methyltransferase

Gene

tam

Organism
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / JCM 21032 / NBRC 15819 / NCTC 12168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-3-(methoxycarbonyl)pent-2-enedioate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciOANT439375:GJIT-1747-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Trans-aconitate 2-methyltransferaseUniRule annotation (EC:2.1.1.144UniRule annotation)
Gene namesi
Name:tamUniRule annotation
Ordered Locus Names:Oant_1719
OrganismiOchrobactrum anthropi (strain ATCC 49188 / DSM 6882 / JCM 21032 / NBRC 15819 / NCTC 12168)
Taxonomic identifieri439375 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeOchrobactrum
Proteomesi
  • UP000002301 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 255255Trans-aconitate 2-methyltransferasePRO_1000056570Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliA6WZN1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. Tam family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107R6G. Bacteria.
COG4106. LUCA.
HOGENOMiHOG000125295.
KOiK00598.
OMAiETTYLHV.
OrthoDBiPOG091H08XS.

Family and domain databases

Gene3Di1.10.150.290. 2 hits.
3.40.50.150. 1 hit.
HAMAPiMF_00560. Tran_acon_Me_trans. 1 hit.
InterProiIPR025714. Methyltranfer_dom.
IPR029063. SAM-dependent_MTases.
IPR023506. Trans-aconitate_MeTrfase.
IPR023149. Trans_acon_MeTrfase_C.
[Graphical view]
PfamiPF13847. Methyltransf_31. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

A6WZN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDWSAKQYL KFEDERSRPA RDLLAQIPVD KPRKVVDIGC GPGNSTELLV
60 70 80 90 100
ERWPEADVSG FDTSPDMIEK AKVRLPKVDF TIGDVASYEP DAETDVLFSN
110 120 130 140 150
AVFQWLPDHI KQMKRLLSLL RPGAVLAVQM PDNMGEQTHV GMRDVAKTEA
160 170 180 190 200
FAAKIGAKGR GPLPPVMEYY NALAGQAARL DIWHTVYNHP LDGVDAIVEW
210 220 230 240 250
VKATGLRPFL DPLDEQEQAD YLKAYKARIA PHYPVAVDGK VLLRFPRIFL

VVQKR
Length:255
Mass (Da):28,662
Last modified:August 21, 2007 - v1
Checksum:iBBC95B977FD8C1F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000758 Genomic DNA. Translation: ABS14435.1.
RefSeqiWP_012091728.1. NC_009667.1.

Genome annotation databases

EnsemblBacteriaiABS14435; ABS14435; Oant_1719.
GeneIDi5380969.
KEGGioan:Oant_1719.
PATRICi20468627. VBIOchAnt73124_1816.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000758 Genomic DNA. Translation: ABS14435.1.
RefSeqiWP_012091728.1. NC_009667.1.

3D structure databases

ProteinModelPortaliA6WZN1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABS14435; ABS14435; Oant_1719.
GeneIDi5380969.
KEGGioan:Oant_1719.
PATRICi20468627. VBIOchAnt73124_1816.

Phylogenomic databases

eggNOGiENOG4107R6G. Bacteria.
COG4106. LUCA.
HOGENOMiHOG000125295.
KOiK00598.
OMAiETTYLHV.
OrthoDBiPOG091H08XS.

Enzyme and pathway databases

BioCyciOANT439375:GJIT-1747-MONOMER.

Family and domain databases

Gene3Di1.10.150.290. 2 hits.
3.40.50.150. 1 hit.
HAMAPiMF_00560. Tran_acon_Me_trans. 1 hit.
InterProiIPR025714. Methyltranfer_dom.
IPR029063. SAM-dependent_MTases.
IPR023506. Trans-aconitate_MeTrfase.
IPR023149. Trans_acon_MeTrfase_C.
[Graphical view]
PfamiPF13847. Methyltransf_31. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTAM_OCHA4
AccessioniPrimary (citable) accession number: A6WZN1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: September 7, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.