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A6WYV7 (DADA_OCHA4) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
D-amino acid dehydrogenase small subunit

EC=1.4.99.1
Gene names
Name:dadA
Ordered Locus Names:Oant_1444
OrganismOchrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168) [Complete proteome] [HAMAP]
Taxonomic identifier439375 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeOchrobactrum

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202

Catalytic activity

A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202

Cofactor

FAD By similarity. HAMAP MF_01202

Pathway

Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202

Subunit structure

Heterodimer of a small and a large subunit By similarity.

Sequence similarities

Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionD-amino-acid dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 416416D-amino acid dehydrogenase small subunit HAMAP MF_01202
PRO_1000066102

Regions

Nucleotide binding3 – 1715FAD Potential

Sequences

Sequence LengthMass (Da)Tools
A6WYV7 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: D535372236B10A2B

FASTA41645,136
        10         20         30         40         50         60 
MQITILGSGV IGVTTAYYLA KLGHEVTVVD REEGPALETS FANAGQVSPG YASPWAAPGI 

        70         80         90        100        110        120 
PFKAAKWLFQ KHAPLVLRPT CDPVQYSWLL QMLANCTDSR YKVNKTRMVR VAEYARDCLV 

       130        140        150        160        170        180 
DLRKETGIEY DQRMQGTLQL FREQYQLDGI GKDIEVLRQD GVPFEVLDRE GCAKVEPALA 

       190        200        210        220        230        240 
RVKDKFVGGL RLPHDETGDC FKFTNALAKI AEGLGVKFRF GVNIKSLLMS GGKVSGVETS 

       250        260        270        280        290        300 
EGVLTADRYV VALGSYTPAL VKSLGLNAPI YPVKGYSITA PIVDEDRAPV STVLDESYKI 

       310        320        330        340        350        360 
AITRLGDRIR VGGMAEVSGF TTDLPAARRA TLDLSVTDLF PGGDLKAATF WSGLRPMTPD 

       370        380        390        400        410 
STPIIGATRY DNVFINAGHG TLGWTMSCGS GKLLADLISG NKPDIRADDL GISRYE 

« Hide

References

[1]"Complete sequence of chromosome 1 of Ochrobactrum anthropi ATCC 49188."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Garcia E., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49188 / DSM 6882 / NCTC 12168.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000758 Genomic DNA. Translation: ABS14161.1.
RefSeqYP_001369990.1. NC_009667.1.

3D structure databases

ProteinModelPortalA6WYV7.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6WYV7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5380437.
GenomeReviewsGene locus Oant_1444 in contig CP000758_GR.
KEGGoan:Oant_1444.
PATRIC20468017. VBIOchAnt73124_1513.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0665.
HOGENOMHBG729204.
OMAVDRQPAV.
ProtClustDBPRK00711.

Enzyme and pathway databases

BioCycOANT439375:OANT_1444-MONOMER.

Family and domain databases

HAMAPMF_01202. DadA.
[Tree]
InterProIPR023080. D-aa_DH_ssu_DadA.
IPR006076. FAD-dep_OxRdtase.
[Graphical view]
KOK00285.
PfamPF01266. DAO. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDADA_OCHA4
AccessionPrimary (citable) accession number: A6WYV7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 21, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families