Reviewed, UniProtKB/Swiss-Prot A6WYV7 (DADA_OCHA4)

Names and origin

Protein names

Recommended name:
    D-amino acid dehydrogenase small subunit
    EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	Oant_1444

Organism

Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168) [Complete proteome] [HAMAP]

Taxonomic identifier

439375 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Ochrobactrum

Protein attributes

Sequence length	416 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity.
Catalytic activity	A D-amino acid + H(2)O + acceptor = a 2-oxo acid + NH(3) + reduced acceptor.
Cofactor	FAD By similarity.
Pathway	Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1.
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the dadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	alanine catabolic process Inferred from electronic annotation. Source: HAMAP oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 416	416	D-amino acid dehydrogenase small subunit		PRO_1000066102
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	A6WYV7-1 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: D535372236B10A2B	FASTA	416	45,136
	10 20 30 40 50 60 MQITILGSGV IGVTTAYYLA KLGHEVTVVD REEGPALETS FANAGQVSPG YASPWAAPGI 70 80 90 100 110 120 PFKAAKWLFQ KHAPLVLRPT CDPVQYSWLL QMLANCTDSR YKVNKTRMVR VAEYARDCLV 130 140 150 160 170 180 DLRKETGIEY DQRMQGTLQL FREQYQLDGI GKDIEVLRQD GVPFEVLDRE GCAKVEPALA 190 200 210 220 230 240 RVKDKFVGGL RLPHDETGDC FKFTNALAKI AEGLGVKFRF GVNIKSLLMS GGKVSGVETS 250 260 270 280 290 300 EGVLTADRYV VALGSYTPAL VKSLGLNAPI YPVKGYSITA PIVDEDRAPV STVLDESYKI 310 320 330 340 350 360 AITRLGDRIR VGGMAEVSGF TTDLPAARRA TLDLSVTDLF PGGDLKAATF WSGLRPMTPD 370 380 390 400 410 STPIIGATRY DNVFINAGHG TLGWTMSCGS GKLLADLISG NKPDIRADDL GISRYE

References

[1]

"Complete sequence of chromosome 1 of Ochrobactrum anthropi ATCC 49188." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Garcia E., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000758 Genomic DNA. Translation: ABS14161.1.
RefSeq	YP_001369990.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5380437.
GenomeReviews	Gene locus Oant_1444 in contig CP000758_GR.
KEGG	oan:Oant_1444.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_01202. [Tree]
InterPro	IPR006076. FAD-dep_OxRdtase. [Graphical view]
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProDom	PD000139. FAD_pyr_redox. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

DADA_OCHA4

Accession

Primary (citable) accession number: A6WYV7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	August 21, 2007
Last modified:	November 4, 2008
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)