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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / JCM 21032 / NBRC 15819 / NCTC 12168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. Fructose-bisphosphate aldolase (Oant_1185)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei353Proton donorUniRule annotation1
Active sitei384UniRule annotation1
Active sitei513UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciOANT439375:G1G9F-393-MONOMER
UniPathwayiUPA00109; UER00181
UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Oant_0369
OrganismiOchrobactrum anthropi (strain ATCC 49188 / DSM 6882 / JCM 21032 / NBRC 15819 / NCTC 12168)
Taxonomic identifieri439375 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeOchrobactrum
Proteomesi
  • UP000002301 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000139931 – 549Glucose-6-phosphate isomeraseAdd BLAST549

Proteomic databases

PRIDEiA6WVU6

Interactioni

Protein-protein interaction databases

STRINGi439375.Oant_0369

Structurei

3D structure databases

ProteinModelPortaliA6WVU6
SMRiA6WVU6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.101 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

A6WVU6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARDATKLEA TVAKLKKHWA DSAPHDMRAA FKSDPGRFER YSLSLDDLLF
60 70 80 90 100
DWSKCRVNDE TIGLLKELAI AADVEGRRAA MFAGEHINNT EDRAVLHVAL
110 120 130 140 150
RDTSSKEVLV DGHNVLPDVK EVLDRMAAFA DGIRSGAIKG ATGKKITDIV
160 170 180 190 200
NIGIGGSDLG PVMATLALSP YHDGPRAHFV SNIDGAHIAD TLGILDPATT
210 220 230 240 250
LVIIASKTFT TIETMTNAQT ARKWVADALG EAAVGAHFAA VSTALDRVAA
260 270 280 290 300
FGIAEDRVFG FWDWVGGRYS VWSAIGLPVM IAIGPEDFRK FLAGAHSMDV
310 320 330 340 350
HFRDAPLEKN LAVWLGLIGY WHRAICGYGS RAIIPYDQRL ARLPAYLQQL
360 370 380 390 400
DMESNGKSVT VDGKPVSGPT GPVVWGEPGT NGQHAFFQLL HQGTDTIPLE
410 420 430 440 450
FIVAAKGHEK HLDHQHEMLL ANCLAQSEAL MKGRTLDEAR AQLKAKNLPE
460 470 480 490 500
SEVERIAPHR VFSGNRPSLT LVHDKLDPFA LGRLVALYEH RVFVEAQIFG
510 520 530 540
INAFDQWGVE LGKELATELL PVVSGEESSD GRDASTQGLV AHLHARRKA
Length:549
Mass (Da):59,734
Last modified:August 21, 2007 - v1
Checksum:iAAE345733D237F17
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000758 Genomic DNA Translation: ABS13100.1
RefSeqiWP_012090690.1, NC_009667.1

Genome annotation databases

EnsemblBacteriaiABS13100; ABS13100; Oant_0369
GeneIDi5379944
KEGGioan:Oant_0369
PATRICifig|439375.7.peg.392

Similar proteinsi

Entry informationi

Entry nameiG6PI_OCHA4
AccessioniPrimary (citable) accession number: A6WVU6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: February 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome