A6WV84 (GLND_OCHA4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	Oant_0157

Organism

Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168) [Complete proteome] [HAMAP]

Taxonomic identifier

439375 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Ochrobactrum › Ochrobactrum anthropi

Protein attributes

Sequence length	934 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nitrogen fixation Inferred from electronic annotation. Source: HAMAP
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 934	934	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_1000022349

Sequences

	Sequence		Length	Mass (Da)
	A6WV84 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: E614E52BF69FF8E3	FASTA	934	105,778
	10 20 30 40 50 60 MSAHDLKLEE IVNPETLRRK LNELADSTDE NYTSPTVRKV VLQALKDALV RGRANAEGML 70 80 90 100 110 120 MKDGGGTLCA KRLSFLMDTL IEALFEFATT KAYPMINPSK AENMAIVAVG GYGRGGLAPG 130 140 150 160 170 180 SDIDLLFLLP YKQTPWGEQV VEYMLYMLWD MGLKVGHSTR NIDECIRLSR EDMTIRTAIL 190 200 210 220 230 240 DARFLTGNRE LFKTLVTRFD EEIVKDTGPE FIQAKLAERD QRHRKAGETR YLVEPNVKEG 250 260 270 280 290 300 KGGQRDLHTL FWITKYFYRV KTKEELVKLG VLSRAELKLF NKAEDFLWAV RCHMHFATLK 310 320 330 340 350 360 AEERLSFDIQ PEIAQRLGYT AHPGQNYVER FMKHYFLVAK DVGDLTRIIS AALEEQQAKH 370 380 390 400 410 420 VPGFNRIFLT FSRRKRKLSA DGDFVSENHR INIARPEVFK EDPVNIIRLF HLADKHGLEF 430 440 450 460 470 480 HPEAMQSLTR SLKLINSDLR ENPEANKLFL EILTSPRNPE LILRRMNESG VLGKFIPDFG 490 500 510 520 530 540 KIVAMMQFNM YHHYTVDEHL LRCIAVLSEI EHGELENEHP LSNHLITTVK RDRNLLYVAL 550 560 570 580 590 600 LLHDIAKGRP EDHSVAGARI ARRLGPRLGL TPTETETVEW LVREHLTMSM VAQSRDLNDR 610 620 630 640 650 660 KTIIDFADTV QTMERLKLLL ILTVCDIKAV GPGVWNGWKG QLLRTLFYET ELVLTGGFSE 670 680 690 700 710 720 LSRADRDHQA REALADRLSD WPKDKRDAYL ALHYTNYFLT VSLEDQVRHA HFIREADRNE 730 740 750 760 770 780 RALATMAKPH TFEAVTEITV LAPDHPRLLS IITGACAAAG ANIVDAQIFT TGDGRALDTI 790 800 810 820 830 840 LISREFDTDD DERRRAERVG KVIEDVLSGK AHLPDVLAKR TKPKRAAKAF KVEPRVEINN 850 860 870 880 890 900 TLSNKFTVIE VEGLDRPGLL SELTGLISDL SLDIASAHIT TFGEKVIDSF YVTDLVGHKI 910 920 930 SNATRQGNIR RKLLGVLSGE NGSKTNGRSS QAAA

References

[1]

"Genome of Ochrobactrum anthropi ATCC 49188 T, a versatile opportunistic pathogen and symbiont of several eukaryotic hosts." Chain P.S., Lang D.M., Comerci D.J., Malfatti S.A., Vergez L.M., Shin M., Ugalde R.A., Garcia E., Tolmasky M.E. J. Bacteriol. 193:4274-4275(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49188 / DSM 6882 / NCTC 12168.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000758 Genomic DNA. Translation: ABS12888.1.
RefSeq	YP_001368717.1. NC_009667.1.
3D structure databases
ProteinModelPortal	A6WV84.
ModBase	Search...
Protein-protein interaction databases
STRING	439375.Oant_0157.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABS12888; ABS12888; Oant_0157.
GeneID	5379798.
KEGG	oan:Oant_0157.
PATRIC	20465277. VBIOchAnt73124_0167.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261779.
KO	K00990.
OMA	SPKVWNA.
ProtClustDB	PRK05092.
Enzyme and pathway databases
BioCyc	OANT439375:GJIT-159-MONOMER.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_OCHA4

Accession

Primary (citable) accession number: A6WV84

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 21, 2007
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program