Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A6WV52

- PNCB_OCHA4

UniProt

A6WV52 - PNCB_OCHA4

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
  3. nicotinate phosphoribosyltransferase activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciOANT439375:GJIT-127-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotation (EC:6.3.4.21UniRule annotation)
Short name:
NAPRTaseUniRule annotation
Gene namesi
Name:pncBUniRule annotation
Ordered Locus Names:Oant_0125
OrganismiOchrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168)
Taxonomic identifieri439375 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeOchrobactrum
ProteomesiUP000002301: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 434434Nicotinate phosphoribosyltransferasePRO_1000025003Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi439375.Oant_0125.

Structurei

3D structure databases

ProteinModelPortaliA6WV52.
SMRiA6WV52. Positions 1-426.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284929.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

A6WV52-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKTDIARRV YNHAWKLDPI VRSLLDTDFY KLLMLQMIWG LYPKVDATFS
60 70 80 90 100
LINRTTSVRL ADEIDEGELR AQLDHARTLR FSKKEMIWLA GNSFYGRKQI
110 120 130 140 150
FQPEFLNWLH DFQLPEYDLR RKDGQYELHF HGPWSHTTMW EIPALAIINE
160 170 180 190 200
LRSRAAMKNL GPFSLDVLYA RAKAKMWSKV ERLRQLPGLK ISDFGTRRRH
210 220 230 240 250
SFLWQRWCVE ALKEGIGDAF TGTSNVLLAM DTDLEALGTN AHELPMVLAA
260 270 280 290 300
LAKNDEELRS APYRVLQDWN RYYGGNLLIV LPDAFGTAAF LRNAPDWVAD
310 320 330 340 350
WTGFRPDSAP PIEGGERIIE WWKSRGKDPR EKLLIFSDAL DVDTIEETYR
360 370 380 390 400
HFEGRVRMSF GWGTNLTNDF AGCAPKEIEG LNAISLVCKV TDANGHPAVK
410 420 430
LSDNPQKATG DPKEVARYLK FFGNEERVEQ LVRV
Length:434
Mass (Da):49,921
Last modified:August 21, 2007 - v1
Checksum:i53753B7439871B21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000758 Genomic DNA. Translation: ABS12856.1.
RefSeqiYP_001368685.1. NC_009667.1.

Genome annotation databases

EnsemblBacteriaiABS12856; ABS12856; Oant_0125.
GeneIDi5378787.
KEGGioan:Oant_0125.
PATRICi20465209. VBIOchAnt73124_0133.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000758 Genomic DNA. Translation: ABS12856.1 .
RefSeqi YP_001368685.1. NC_009667.1.

3D structure databases

ProteinModelPortali A6WV52.
SMRi A6WV52. Positions 1-426.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 439375.Oant_0125.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABS12856 ; ABS12856 ; Oant_0125 .
GeneIDi 5378787.
KEGGi oan:Oant_0125.
PATRICi 20465209. VBIOchAnt73124_0133.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284929.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci OANT439375:GJIT-127-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome of Ochrobactrum anthropi ATCC 49188 T, a versatile opportunistic pathogen and symbiont of several eukaryotic hosts."
    Chain P.S., Lang D.M., Comerci D.J., Malfatti S.A., Vergez L.M., Shin M., Ugalde R.A., Garcia E., Tolmasky M.E.
    J. Bacteriol. 193:4274-4275(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49188 / DSM 6882 / NCTC 12168.

Entry informationi

Entry nameiPNCB_OCHA4
AccessioniPrimary (citable) accession number: A6WV52
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: October 1, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3