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A6WTS0

- ASSY_SHEB8

UniProt

A6WTS0 - ASSY_SHEB8

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Protein
Argininosuccinate synthase
Gene
argG, Shew185_4092
Organism
Shewanella baltica (strain OS185)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei44 – 441ATP; via amide nitrogen and carbonyl oxygen By similarity
Binding sitei96 – 961Citrulline By similarity
Binding sitei101 – 1011Citrulline By similarity
Binding sitei126 – 1261ATP; via amide nitrogen By similarity
Binding sitei128 – 1281Aspartate By similarity
Binding sitei132 – 1321Aspartate By similarity
Binding sitei132 – 1321Citrulline By similarity
Binding sitei133 – 1331Aspartate By similarity
Binding sitei136 – 1361Citrulline By similarity
Binding sitei185 – 1851Citrulline By similarity
Binding sitei194 – 1941Citrulline By similarity
Binding sitei270 – 2701Citrulline By similarity
Binding sitei282 – 2821Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 249ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. argininosuccinate synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSBAL402882:GJ99-4225-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:Shew185_4092
OrganismiShewanella baltica (strain OS185)
Taxonomic identifieri402882 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000006387: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 412412Argininosuccinate synthaseUniRule annotation
PRO_1000000432Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi402882.Shew185_4092.

Structurei

3D structure databases

ProteinModelPortaliA6WTS0.
SMRiA6WTS0. Positions 12-405.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiAPPEEAY.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6WTS0-1 [UniParc]FASTAAdd to Basket

« Hide

MSIEIKNTGV KKVVLAYSGG LDTSAIIPWL KENYDNCEII AFCADVGQGE    50
EELVGLTEKA LASGASECHI VDLKEEFVKE YIYPTIASGA IYEGTYLLGT 100
SMARPIIAKA QVEVARKVGA DALCHGCTGK GNDQVRFEGC FAALAPDLKV 150
IAPWREWTMQ SREDLLAYLA ERDIKTSASA TKIYSRDANA FHISHEGGEL 200
EDPWNEPSKG VWTLTADPED APNKPEYVSL EVEHGRITKV NGEALTPYAA 250
LMTLNAIAAP HGVGRIDITE NRLVGMKSRG CYETPGGTVM FAALRAIEEL 300
VLDKTSRNWR EQVAAQMAHL VYDGRWFTPL CKSLLAASES LAESVNGEVV 350
VKLYKGQATA VKKRSPNSLY SEAFATFGED QVYDQKHAEG FIRLYSLASR 400
IRALNANDVK SK 412
Length:412
Mass (Da):45,079
Last modified:August 21, 2007 - v1
Checksum:i067026B7E4F1448C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000753 Genomic DNA. Translation: ABS10209.1.
RefSeqiYP_001368272.1. NC_009665.1.

Genome annotation databases

EnsemblBacteriaiABS10209; ABS10209; Shew185_4092.
GeneIDi5372054.
KEGGisbm:Shew185_4092.
PATRICi23465285. VBISheBal127872_4377.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000753 Genomic DNA. Translation: ABS10209.1 .
RefSeqi YP_001368272.1. NC_009665.1.

3D structure databases

ProteinModelPortali A6WTS0.
SMRi A6WTS0. Positions 12-405.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 402882.Shew185_4092.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABS10209 ; ABS10209 ; Shew185_4092 .
GeneIDi 5372054.
KEGGi sbm:Shew185_4092.
PATRICi 23465285. VBISheBal127872_4377.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi APPEEAY.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci SBAL402882:GJ99-4225-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: OS185.

Entry informationi

Entry nameiASSY_SHEB8
AccessioniPrimary (citable) accession number: A6WTS0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: May 14, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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