A6WQD3 (GLMM2_SHEB8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase 2
EC=5.4.2.10

Gene names

Name:	glmM2
Ordered Locus Names:	Shew185_2888

Organism

Shewanella baltica (strain OS185) [Complete proteome] [HAMAP]

Taxonomic identifier

402882 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	450 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 450	450	Phosphoglucosamine mutase 2 HAMAP MF_01554_B		PRO_0000343598
Sites
	Active site	101	1	Phosphoserine intermediate By similarity
	Metal binding	101	1	Magnesium; via phosphate group By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
	Metal binding	249	1	Magnesium By similarity
Amino acid modifications
	Modified residue	101	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A6WQD3 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 86220AB0613B8EEE	FASTA	450	47,851
	10 20 30 40 50 60 MSRKYFGTDG VRGKVGEFPI TPDFAMKLGW AAGTVLASTG TKEVLIGKDT RSSGYMLESA 70 80 90 100 110 120 MEAGFSAAGV NVALIGPMPT PAVAYLASTF RADAGVVISA SHNPFYDNGI KFFSNSGTKL 130 140 150 160 170 180 NDAQELEIEA LLEKALNQNA MQCVASEKLG KVRRIDDAAG RYIEFCKGTF PNHLSLAGLK 190 200 210 220 230 240 IVIDSAHGAA YHIAPNVYRE LGAEVISIND KPNGVNINDH CGATHLDSLQ TAVMVHEADL 250 260 270 280 290 300 GIALDGDADR VMFVDHNGHV VDGDEILFIL AQAAHSKGEM TGGVVGTLMS NLGLELALKQ 310 320 330 340 350 360 MDIPFVRAKV GDRYVVEQLK RTGWQLGGEG SGHILSLQHA STGDGIVASL QVLKAVLESQ 370 380 390 400 410 420 KSLSEIKAGM TKLPQVLINV RLATADADSI LATTSVKQAV IKAEEFLGDQ GRVLLRKSGT 430 440 450 EPLIRVMVES TDNIMTQTQA EYIADAVRAA

References

[1]

"Complete sequence of chromosome of Shewanella baltica OS185." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Brettar I., Rodrigues J., Konstantinidis K., Tiedje J., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OS185.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000753 Genomic DNA. Translation: ABS09022.1.
RefSeq	YP_001367085.1. NC_009665.1.
3D structure databases
ProteinModelPortal	A6WQD3.
ModBase	Search...
Protein-protein interaction databases
STRING	A6WQD3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5369563.
GenomeReviews	Gene locus Shew185_2888 in contig CP000753_GR.
KEGG	sbm:Shew185_2888.
PATRIC	23462717. VBISheBal127872_3128.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	ESTDNIM.
ProtClustDB	CLSK2516801.
Enzyme and pathway databases
BioCyc	SBAL402882:SHEW185_2888-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM2_SHEB8

Accession

Primary (citable) accession number: A6WQD3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 22, 2008
Last sequence update:	August 21, 2007
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program