A6WMX7 (A6WMX7_SHEB8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163

Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163

Gene names

Name:	def2 HAMAP MF_00163
Ordered Locus Names:	Shew185_2023

Organism

Shewanella baltica (strain OS185) [Complete proteome] [HAMAP] EMBL ABS08166.1

Taxonomic identifier

402882 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	163 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163
Catalytic activity	Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181
Cofactor	Binds 1 Fe2+ ion By similarity. HAMAP MF_00163
Sequence similarities	Belongs to the polypeptide deformylase family. HAMAP MF_00163

Ontologies

Keywords
Biological process	Protein biosynthesis SAAS SAAS000181 HAMAP MF_00163
Ligand	Iron HAMAP MF_00163 Metal-binding HAMAP MF_00163 SAAS SAAS000181
Molecular function	Hydrolase HAMAP MF_00163 SAAS SAAS000181 EMBL ABS08166.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro peptide deformylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	134	1	By similarity HAMAP MF_00163
	Metal binding	91	1	Iron By similarity HAMAP MF_00163
	Metal binding	133	1	Iron By similarity HAMAP MF_00163
	Metal binding	137	1	Iron By similarity HAMAP MF_00163

Sequences

	Sequence		Length	Mass (Da)
	A6WMX7 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 734F0012EA73D18A	FASTA	163	18,163
	10 20 30 40 50 60 MAVLDILTIP DERLKRKAQP VKDIEAVQGF IDDLIETMYH TDDGIGLAAT QVGSTDAIIV 70 80 90 100 110 120 IDLSDGRDQP QVLINPEIVE KSGEFVGEEG CLSIPGYRAK VSRFEKVKVT ALDRTGKAIE 130 140 150 160 IETDEFLAIV LQHEIDHLHG KVFIEHLSML KQQIALKKVR KYA

References

[1]

"Complete sequence of chromosome of Shewanella baltica OS185." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Brettar I., Rodrigues J., Konstantinidis K., Tiedje J., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OS185.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000753 Genomic DNA. Translation: ABS08166.1.
RefSeq	YP_001366229.1. NC_009665.1.
3D structure databases
ProteinModelPortal	A6WMX7.
SMR	A6WMX7. Positions 2-162.
ModBase	Search...
Protein-protein interaction databases
STRING	A6WMX7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5369622.
GenomeReviews	Gene locus Shew185_2023 in contig CP000753_GR.
KEGG	sbm:Shew185_2023.
PATRIC	23460798. VBISheBal127872_2217.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0242.
HOGENOM	HBG665227.
OMA	MINAHIE.
ProtClustDB	PRK12846.
Enzyme and pathway databases
BioCyc	SBAL402882:SHEW185_2023-MONOMER.
Family and domain databases
HAMAP	MF_00163. Pep_deformylase. [Tree]
InterPro	IPR000181. Fmet_deformylase. IPR023635. Peptide_deformylase. [Graphical view]
Gene3D	G3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KO	K01462.
PANTHER	PTHR10458. Fmet_deformylase. 1 hit.
Pfam	PF01327. Pep_deformylase. 1 hit. [Graphical view]
PIRSF	PIRSF004749. Pep_def. 1 hit.
PRINTS	PR01576. PDEFORMYLASE.
SUPFAM	SSF56420. Fmet_deformylase. 1 hit.
TIGRFAMs	TIGR00079. Pept_deformyl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6WMX7_SHEB8

Accession

Primary (citable) accession number: A6WMX7

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)