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A6WKR1

- ACPS_SHEB8

UniProt

A6WKR1 - ACPS_SHEB8

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Protein

Holo-[acyl-carrier-protein] synthase

Gene

acpS

Organism
Shewanella baltica (strain OS185)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.UniRule annotation

Catalytic activityi

CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein].UniRule annotation

Cofactori

Magnesium.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi9 – 91MagnesiumUniRule annotation
Metal bindingi58 – 581MagnesiumUniRule annotation

GO - Molecular functioni

  1. holo-[acyl-carrier-protein] synthase activity Source: UniProtKB-HAMAP
  2. magnesium ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-HAMAP
  2. macromolecule biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciSBAL402882:GJ99-1284-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Holo-[acyl-carrier-protein] synthaseUniRule annotation (EC:2.7.8.7UniRule annotation)
Short name:
Holo-ACP synthaseUniRule annotation
Alternative name(s):
4'-phosphopantetheinyl transferase AcpSUniRule annotation
Gene namesi
Name:acpSUniRule annotation
Ordered Locus Names:Shew185_1249
OrganismiShewanella baltica (strain OS185)
Taxonomic identifieri402882 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000006387: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 127127Holo-[acyl-carrier-protein] synthasePRO_1000008491Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi402882.Shew185_1249.

Structurei

3D structure databases

ProteinModelPortaliA6WKR1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the P-Pant transferase superfamily. AcpS family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0736.
HOGENOMiHOG000014316.
KOiK00997.
OMAiNGRFAEK.
OrthoDBiEOG6384R9.

Family and domain databases

Gene3Di3.90.470.20. 1 hit.
HAMAPiMF_00101. AcpS.
InterProiIPR008278. 4-PPantetheinyl_Trfase_SF.
IPR002582. ACPS.
IPR004568. PPantethiene-prot_Trfase_dom.
[Graphical view]
PfamiPF01648. ACPS. 1 hit.
[Graphical view]
ProDomiPD004282. PPantethiene-prot_Trfase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF56214. SSF56214. 1 hit.
TIGRFAMsiTIGR00516. acpS. 1 hit.
TIGR00556. pantethn_trn. 1 hit.

Sequencei

Sequence statusi: Complete.

A6WKR1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAIVGLGTDI VEIERIQAHV ARAGDKLAKR VLTEAELAIY TAHSQPSRYL
60 70 80 90 100
AKRFAAKEAA AKALGTGIGR GVSFQHIHIG NNEDGAPTIH FTEGALTRLQ
110 120
QLKATVGHIS IADEKSYAIA TVIIESQ
Length:127
Mass (Da):13,556
Last modified:August 21, 2007 - v1
Checksum:i8F35A46D3ABF7D90
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000753 Genomic DNA. Translation: ABS07400.1.
RefSeqiWP_012088606.1. NC_009665.1.
YP_001365463.1. NC_009665.1.

Genome annotation databases

EnsemblBacteriaiABS07400; ABS07400; Shew185_1249.
GeneIDi5372258.
KEGGisbm:Shew185_1249.
PATRICi23459157. VBISheBal127872_1409.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000753 Genomic DNA. Translation: ABS07400.1 .
RefSeqi WP_012088606.1. NC_009665.1.
YP_001365463.1. NC_009665.1.

3D structure databases

ProteinModelPortali A6WKR1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 402882.Shew185_1249.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABS07400 ; ABS07400 ; Shew185_1249 .
GeneIDi 5372258.
KEGGi sbm:Shew185_1249.
PATRICi 23459157. VBISheBal127872_1409.

Phylogenomic databases

eggNOGi COG0736.
HOGENOMi HOG000014316.
KOi K00997.
OMAi NGRFAEK.
OrthoDBi EOG6384R9.

Enzyme and pathway databases

BioCyci SBAL402882:GJ99-1284-MONOMER.

Family and domain databases

Gene3Di 3.90.470.20. 1 hit.
HAMAPi MF_00101. AcpS.
InterProi IPR008278. 4-PPantetheinyl_Trfase_SF.
IPR002582. ACPS.
IPR004568. PPantethiene-prot_Trfase_dom.
[Graphical view ]
Pfami PF01648. ACPS. 1 hit.
[Graphical view ]
ProDomi PD004282. PPantethiene-prot_Trfase. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF56214. SSF56214. 1 hit.
TIGRFAMsi TIGR00516. acpS. 1 hit.
TIGR00556. pantethn_trn. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: OS185.

Entry informationi

Entry nameiACPS_SHEB8
AccessioniPrimary (citable) accession number: A6WKR1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 21, 2007
Last modified: October 29, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3