A6WFC0 (A6WFC0_KINRD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase HAMAP MF_00259
EC=2.1.2.10 HAMAP MF_00259

Alternative name(s):
Glycine cleavage system T protein HAMAP MF_00259

Gene names

Name:	gcvT HAMAP MF_00259
Ordered Locus Names:	Krad_4046

Organism

Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) [Complete proteome] [HAMAP] EMBL ABS05509.1

Taxonomic identifier

266940 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Kineosporiineae › Kineosporiaceae › Kineococcus

Protein attributes

Sequence length	391 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259

Ontologies

Keywords
Molecular function	Aminotransferase HAMAP MF_00259 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6WFC0 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: BB44B2C7354A20B8	FASTA	391	40,120
	10 20 30 40 50 60 MAAPRGRDER SPVTTPATTP APPASTPLAD AHAALGASFT DFAGWQMPLR YASDLAEHHA 70 80 90 100 110 120 VRRAAGIFDL SHMGEIRVSG PQAGAALDAA LAGRPSAMAI GRAAYGLLVD HEGGIVDDLV 130 140 150 160 170 180 TYRLGEQEFL VVANAANVEP VVVALADRAR PFDAHVADET ARWALVAVQG PASAAIVGPL 190 200 210 220 230 240 VDADLTALGY YRCAPATLTT GPGAPGVEVL LARTGYTGED GFEVFVPVDD AVAAWDALLA 250 260 270 280 290 300 ATREHGGVPA GLACRDTLRL EAGMPLYGHE LTTATSPFAA GLGRVVKLDK DPGPVGLEAL 310 320 330 340 350 360 QRLAATPPAR VLVGLRGTGR RAPRAGYPVV AGGSPVGEVT SGALSPTLGY PVAMAYVDAA 370 380 390 LSAPGTALAV DVRGTELPVE VVALPFYRRE R

References

[1]

"Complete sequence of chromosome of Kineococcus radiotolerans SRS30216." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Lykidis A., Bagwell C.E., Shimkets L., Berry C.J., Fliermans C., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-149 / DSM 14245 / SRS30216.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000750 Genomic DNA. Translation: ABS05509.1.
RefSeq	YP_001363773.1. NC_009664.2.
3D structure databases
ProteinModelPortal	A6WFC0.
ModBase	Search...
Protein-protein interaction databases
STRING	A6WFC0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5336852.
GenomeReviews	Gene locus Krad_4046 in contig CP000750_GR.
KEGG	kra:Krad_4046.
NMPDR	fig|266940.1.peg.3675.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0404.
HOGENOM	HBG299834.
OMA	MPVQYPL.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6WFC0_KINRD

Accession

Primary (citable) accession number: A6WFC0

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	November 16, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)