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A6WF09 (A6WF09_KINRD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Adenosine deaminase HAMAP MF_00540
EC=3.5.4.4 HAMAP MF_00540
Alternative name(s):
Adenosine aminohydrolase HAMAP MF_00540
Gene names
Name:add HAMAP MF_00540
Ordered Locus Names:Krad_3935
OrganismKineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) [Complete proteome] [HAMAP] EMBL ABS05398.1
Taxonomic identifier266940 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Kineosporiineae › Kineosporiaceae › Kineococcus

Protein attributes

Sequence length372 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Adenosine + H2O = inosine + NH3. HAMAP MF_00540

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP MF_00540

Sequence similarities

Belongs to the adenosine and AMP deaminases family. Adenosine deaminase subfamily. HAMAP MF_00540

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2171Proton donor By similarity HAMAP MF_00540
Metal binding261Zinc; catalytic By similarity HAMAP MF_00540
Metal binding281Zinc; catalytic By similarity HAMAP MF_00540
Metal binding2141Zinc; catalytic By similarity HAMAP MF_00540
Metal binding3121Zinc; catalytic By similarity HAMAP MF_00540
Binding site281Substrate By similarity HAMAP MF_00540
Binding site301Substrate By similarity HAMAP MF_00540
Binding site1871Substrate; via amide nitrogen and carbonyl oxygen By similarity HAMAP MF_00540
Site2381Important for catalytic activity By similarity HAMAP MF_00540

Sequences

Sequence LengthMass (Da)Tools
A6WF09 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: CB2FC79612F61E85

FASTA37239,783
        10         20         30         40         50         60 
MSTPETPTET APTPEQVRRL PKVSLHDHLD GGLRPSTIVE IAAANGHALP TTDPEELGVW 

        70         80         90        100        110        120 
FRDAADSGSL VRYLETFDHT IAVMQDAESL ARVATEAVLD LATDGVVYGE LRYAPEQHLQ 

       130        140        150        160        170        180 
RGLSLDEVVV AVEEGMRRGE QLAAQAGTPI RVGTLVTAMR HADRGLEIAE LALRHRDAGV 

       190        200        210        220        230        240 
VGFDIAGAEI GFPPSNHLAA FDRLHAENFP VTIHAGEAFG LPSIADALHT CGAERIGHGV 

       250        260        270        280        290        300 
RIVEDIEFGE GRDRFGMPAA TLGRLATWVR DRGIVLELCP SSNVQTGAAT SVAEHPITAL 

       310        320        330        340        350        360 
KDLGFSISVN TDNRLMSGTS LSREFSLLVD EAGWDLADVE RATITALSAS FLPFPDRLAL 

       370 
ASDVIRPAYA PA

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References

[1]"Complete sequence of chromosome of Kineococcus radiotolerans SRS30216."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., Bagwell C.E., Shimkets L., Berry C.J., Fliermans C., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-149 / DSM 14245 / SRS30216.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000750 Genomic DNA. Translation: ABS05398.1.
RefSeqYP_001363662.1. NC_009664.2.

3D structure databases

ProteinModelPortalA6WF09.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6WF09.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5336494.
GenomeReviewsGene locus Krad_3935 in contig CP000750_GR.
KEGGkra:Krad_3935.
NMPDRfig|266940.1.peg.3965.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1816.
HOGENOMHBG630382.
OMAPYYMAMN.
ProtClustDBPRK09358.

Family and domain databases

HAMAPMF_00540. A_deaminase.
[Tree]
InterProIPR001365. A/AMP_deaminase_dom.
IPR006330. A_deaminase.
[Graphical view]
KOK01488.
PANTHERPTHR11409:SF21. PTHR11409:SF21. 1 hit.
PfamPF00962. A_deaminase. 1 hit.
[Graphical view]
TIGRFAMsTIGR01430. Aden_deam. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA6WF09_KINRD
AccessionPrimary (citable) accession number: A6WF09
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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