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A6WDM8 (A6WDM8_KINRD) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP MF_00456
EC=2.7.2.11 HAMAP MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP MF_00456
Gene names
Name:proB HAMAP MF_00456
Ordered Locus Names:Krad_3454
OrganismKineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) [Complete proteome] [HAMAP] EMBL ABS04917.1
Taxonomic identifier266940 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Kineosporiineae › Kineosporiaceae › Kineococcus

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. HAMAP MF_00456 SAAS SAAS011529

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. HAMAP MF_00456 SAAS SAAS011529

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. SAAS SAAS011529 HAMAP MF_00456

Subcellular location

Cytoplasm By similarity HAMAP MF_00456 SAAS SAAS011529.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP MF_00456

Contains 1 PUA domain. HAMAP MF_00456 SAAS SAAS011529

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain288 – 36679PUA By similarity HAMAP MF_00456

Sequences

Sequence LengthMass (Da)Tools
A6WDM8 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: DA80B21B43243D5E

FASTA38239,056
        10         20         30         40         50         60 
MSTPSTVTRR EDLARAGRVV VKVGSSSLTT AVGGLDAARL GALVDVLAAR RAGGGEVVLV 

        70         80         90        100        110        120 
SSGAIAAGLA PLGLRKRPRD LASQQAAASV GQGLLLAEYA RAFARAGLTV GQVLLTAEDV 

       130        140        150        160        170        180 
VRRTHYGNAQ RTLERLLSLG VVPVVNENDT VATHEIRFGD NDRLAALVAH LVRADALVLL 

       190        200        210        220        230        240 
SDVDALYDAP PSTPGASRLA TVRGPEDLGG VTVGSAGAAG VGTGGMATKV EAAGIAVAAG 

       250        260        270        280        290        300 
VPALVTSAAL AGDALAGADV GTWFPVTATG RARRSTRQLW LAHAAAPAGR LVLDEGAVRA 

       310        320        330        340        350        360 
VRQARSSLLP AGVVGLSGRF RAGDPVDLVD GNGHALARGL VNYSSEELPD LLGRSTRELA 

       370        380 
RQWGPAYERE VVHRDHLVLL GR

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References

[1]"Complete sequence of chromosome of Kineococcus radiotolerans SRS30216."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., Bagwell C.E., Shimkets L., Berry C.J., Fliermans C., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-149 / DSM 14245 / SRS30216.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000750 Genomic DNA. Translation: ABS04917.1.
RefSeqYP_001363181.1. NC_009664.2.

3D structure databases

ProteinModelPortalA6WDM8.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6WDM8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5334909.
GenomeReviewsGene locus Krad_3454 in contig CP000750_GR.
KEGGkra:Krad_3454.
NMPDRfig|266940.1.peg.4575.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0263.
HOGENOMHBG507643.
OMATFGDNDM.

Family and domain databases

HAMAPMF_00456. ProB.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00931.
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR01027. ProB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA6WDM8_KINRD
AccessionPrimary (citable) accession number: A6WDM8
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: November 16, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info