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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei136GTPUniRule annotation1
Binding sitei140GTPUniRule annotation1
Binding sitei184GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 22GTPUniRule annotation5
Nucleotide bindingi105 – 107GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Krad_3196Imported
OrganismiKineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)Imported
Taxonomic identifieri266940 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaKineosporialesKineosporiaceaeKineococcus
Proteomesi
  • UP000001116 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi266940.Krad_3196

Structurei

3D structure databases

ProteinModelPortaliA6WCX1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 202TubulinInterPro annotationAdd BLAST193
Domaini204 – 321Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.201 hit
3.40.50.14401 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

A6WCX1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPQNYLAV IKVVGVGGGG VNAVNRMIEV GLKGVEFIAV NTDAQALLMS
60 70 80 90 100
DADVKLDVGR ELTRGLGAGA DPEVGRKAAE DHAEEIEEVL KGADMVFVTA
110 120 130 140 150
GEGGGTGTGG APVVARIARS LGALTIGVVT RPFTFEGRRR ANSAESGIAE
160 170 180 190 200
LRDEVDTLIV IPNDRLLSIS DKQVSILDAF KSADQVLLSG VQGITDLITT
210 220 230 240 250
PGLINLDFAD VKSVMQGAGS ALMGIGSARG DDRAVQAAES AISSPLLEAS
260 270 280 290 300
IDGAHGVLLS IQGGSDLGLY EINEAARLVQ EAAHPEANII FGAVIDDALG
310 320 330 340 350
DEVRVTVIAA GFDSGTPVRR RDERALGQVS GRPQQGSAVP PRTTRPDAWG
360 370 380 390 400
APAAPAAPAP QYQQQEQPPA PAPAPQPQYA QAQQAPSRPY GQQEYVPSQY
410 420 430 440 450
GQPAYGQQPP AAPQQQQAPQ QPAPQPVAHQ APQVVPSEDP VQVPRIIELP
460 470
QDNASVRRPG RPRPEEDDLD VPDFLK
Length:476
Mass (Da):49,672
Last modified:August 21, 2007 - v1
Checksum:iB30BD6AC174B64C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000750 Genomic DNA Translation: ABS04660.1

Genome annotation databases

EnsemblBacteriaiABS04660; ABS04660; Krad_3196
KEGGikra:Krad_3196

Similar proteinsi

Entry informationi

Entry nameiA6WCX1_KINRD
AccessioniPrimary (citable) accession number: A6WCX1
Entry historyiIntegrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: March 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported