A6WCW2 (A6WCW2_KINRD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase III, alpha subunit EMBL ABS04651.1
EC=2.7.7.7 EMBL ABS04651.1

Gene names

Ordered Locus Names:

Krad_3187

Organism

Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) [Complete proteome] [HAMAP] EMBL ABS04651.1

Taxonomic identifier

266940 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Kineosporiineae › Kineosporiaceae › Kineococcus

Protein attributes

Sequence length	1180 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Cellular component	Cytoplasm SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6WCW2 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: FA16496D1777F41E	FASTA	1,180	129,769
	10 20 30 40 50 60 MASADSFAHL HVHTEYSMLD GAAKVDDLFR TAAEMGMPAV ATTDHGFVFG AYDFWKTAKK 70 80 90 100 110 120 HGVKPIIGVE AYLTPGTARQ DKTRVKWGDP NGRSGDDVSG AGSYTHMTML AQNTAGMHNL 130 140 150 160 170 180 FKMSSLASLE GFLYKPRMDR ELLSQYSAGL IATTGCPSGE VQTRLRLGQY DEARKAAADY 190 200 210 220 230 240 RDIFGAENFF CELMDHGLDI ERRVQDDLLK LAKDLDLPLL ATNDLHYTHA GDSQAHAALL 250 260 270 280 290 300 CVQSGSTLAD PKRFKFDADE FYLKSPAEMR HVWRDHPEAC DNTLLIAERC EVEFTESTGA 310 320 330 340 350 360 YMPRFPCPEG EDEESWFVKE VWSGLAQRYP AGIPDDVRKQ ADYEIEVITS KGYAGYFLVV 370 380 390 400 410 420 ADFINWSKEN GIRVGPGRGS GAGSMAAYAM KITDLDPLRH GLFFERFLNP ERMSMPDFDV 430 440 450 460 470 480 DFDERRRGEV IQYVVEKYGT DRVAQIVTYG TIKAKQAVKD SSRVLGFPFS MGDRITKTMP 490 500 510 520 530 540 PAVMGKDIPL SGIFDPNHKR YSEAGEFREL YKSDPEVVKV VDTARGLEGL KRQWGVHAAG 550 560 570 580 590 600 VIMSSDPLID LIPIMKREAD GAIITQFDYP TCETLGLVKM DFLGLRNLTI LDDALKNVVA 610 620 630 640 650 660 NGKEAVDLDA LELDDQATFD LLGRGDTLGV FQFDGGPMRS LLRLMRPDNF EDISAVGALY 670 680 690 700 710 720 RPGPMGAGSH TAYARRKNGQ EPITPIHPEL EEPLKEILGT TYGLIVYQEQ VMSIAQKVAG 730 740 750 760 770 780 YSLGSADLLR RAMGKKKREV LDAEYVGFEK GMLDNGFSKE CVKALWDILV PFSDYAFNKA 790 800 810 820 830 840 HSAAYGLVSY WTAYLKANYP AEYMAAVLTS VRDDKDKSAL YLNECRRMGI QVLPPDVNES 850 860 870 880 890 900 SANFTAVGAD IRFGLTAIRN VGANVVDAVV EARAEKGRYE SFTDFLTKVP AVVCNKRTIE 910 920 930 940 950 960 SLIKAGAFDS LGHRRRALVA KHEDAVDAVV DVKRNEAIGQ FDLFAGLGGD DDGGAGGFHV 970 980 990 1000 1010 1020 EIPDLPEWEK AELLAHERQM LGLYVSDHPL FGLERLLANA SDVPIATLLE DESRPDGSNI 1030 1040 1050 1060 1070 1080 TIAGMITGLQ RKTTKQGNYW AIVTVEDLAG AIECLFFPQA YADVAQLLAE DLVVVVKGRL 1090 1100 1110 1120 1130 1140 NRRDEVPTIY ASGLTVPDIS STDGVPVTVT LPTARCTTQV VEKLKSVLET HAGSTEVRLR 1150 1160 1170 1180 LTRNGGGSGT LMRLDDSLRV TPSPALFGDL KQLLGPACLV

References

[1]

"Complete sequence of chromosome of Kineococcus radiotolerans SRS30216." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Lykidis A., Bagwell C.E., Shimkets L., Berry C.J., Fliermans C., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-149 / DSM 14245 / SRS30216.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000750 Genomic DNA. Translation: ABS04651.1.
RefSeq	YP_001362915.1. NC_009664.2.
3D structure databases
ProteinModelPortal	A6WCW2.
ModBase	Search...
Protein-protein interaction databases
STRING	A6WCW2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5334990.
GenomeReviews	Gene locus Krad_3187 in contig CP000750_GR.
KEGG	kra:Krad_3187.
NMPDR	fig|266940.1.peg.2445.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	RVLQMPY.
ProtClustDB	PRK05673.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6WCW2_KINRD

Accession

Primary (citable) accession number: A6WCW2

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	November 16, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)