A6WCS3 (A6WCS3_KINRD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 2 HAMAP MF_00361
Short name=Poly(P)/ATP NAD kinase 2 HAMAP MF_00361
EC=2.7.1.23 HAMAP MF_00361

Gene names

Name:	ppnK2 HAMAP MF_00361
Ordered Locus Names:	Krad_3148

Organism

Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) [Complete proteome] [HAMAP] EMBL ABS04612.1

Taxonomic identifier

266940 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Kineosporiineae › Kineosporiaceae › Kineococcus

Protein attributes

Sequence length	312 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361
Subcellular location	Cytoplasm By similarity HAMAP MF_00361.
Sequence similarities	Belongs to the NAD kinase family. HAMAP MF_00361

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00361
Ligand	ATP-binding HAMAP MF_00361 NAD HAMAP MF_00361 NADP HAMAP MF_00361 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00361 EMBL ABS04612.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6WCS3 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 3267D9D36D86FF81	FASTA	312	32,642
	10 20 30 40 50 60 MSAPRTGVPQ AARSVLVLAH TGRSQAVSAL TEVVRRFHEA GIRTLMTPDE AAALSVADRA 70 80 90 100 110 120 LVEERDLEGA VAGAEMVIVL GGDGTILRAA ELVRGTATTL LGVNLGHVGF LAEAEREEVV 130 140 150 160 170 180 GTVARVVAAD YRVEERMTLD VQVLLDGQVV ASSWAVNEVS VEKANRERML ELVVDVDGRP 190 200 210 220 230 240 LSTFGADGVI AATPTGSTAY AFSAGGPVVW PEVEALLVVP ISAHALFARP LVIAPTSVVG 250 260 270 280 290 300 IEVLPGMGDG GVLWCDGRRT FAAPAGARVE VRRSPRTIRL ARLSSGAFTD RLVAKFGLPV 310 QGWRGPRSSD GG

References

[1]

"Complete sequence of chromosome of Kineococcus radiotolerans SRS30216." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Lykidis A., Bagwell C.E., Shimkets L., Berry C.J., Fliermans C., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-149 / DSM 14245 / SRS30216.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000750 Genomic DNA. Translation: ABS04612.1.
RefSeq	YP_001362876.1. NC_009664.2.
3D structure databases
ProteinModelPortal	A6WCS3.
SMR	A6WCS3. Positions 13-304.
ModBase	Search...
Protein-protein interaction databases
STRING	A6WCS3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5334585.
GenomeReviews	Gene locus Krad_3148 in contig CP000750_GR.
KEGG	kra:Krad_3148.
NMPDR	fig|266940.1.peg.3868.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0061.
HOGENOM	HBG713904.
OMA	GPVVWPE.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017438. ATP-NAD_kinase_PpnK-typ_a/b. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. polyP/ATP_NADK_prd. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit. G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KO	K00858.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6WCS3_KINRD

Accession

Primary (citable) accession number: A6WCS3

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	November 16, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)