A6W7W5 (EFTS_KINRD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Elongation factor Ts
Short name=EF-Ts

Gene names

Name:	tsf
Ordered Locus Names:	Krad_1416

Organism

Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) [Complete proteome] [HAMAP]

Taxonomic identifier

266940 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Kineosporiineae › Kineosporiaceae › Kineococcus

Protein attributes

Sequence length	275 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome By similarity. HAMAP MF_00050
Subcellular location	Cytoplasm By similarity HAMAP MF_00050.
Sequence similarities	Belongs to the EF-Ts family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 275	275	Elongation factor Ts HAMAP MF_00050		PRO_1000074867
Regions
	Region	80 – 83	4	Involved in Mg(2+) ion dislocation from EF-Tu By similarity

Sequences

	Sequence		Length	Mass (Da)
	A6W7W5 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 611C1949CA177A9A	FASTA	275	29,343
	10 20 30 40 50 60 MAAYTAADVK ALREKTGAGM LDCKNALVES EGDVEKAIEL LRIKGQKGVA KREDRDASNG 70 80 90 100 110 120 LVAVHTDGGL GVMVQLNCET DFVAKSEGFI ALSQQVLDQA VAVAATDAES LLASDLGGRT 130 140 150 160 170 180 VQELLDEANA TMGEKILVPR VARIEGTHVS AYLHRTATDL PPTIGVLVAL DAVNDEIGKD 190 200 210 220 230 240 VAMHTAAMSP TYLTREDVPA EKVESERRIA EETAREENKP EAAMAKIVEG RVNSYFKDNV 250 260 270 LLEQPFAKDP KTTITKLLAG AGVHVTSFAR FRAGA

References

[1]

"Complete sequence of chromosome of Kineococcus radiotolerans SRS30216." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Lykidis A., Bagwell C.E., Shimkets L., Berry C.J., Fliermans C., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-149 / DSM 14245 / SRS30216.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000750 Genomic DNA. Translation: ABS02904.1.
RefSeq	YP_001361168.1. NC_009664.2.
3D structure databases
ProteinModelPortal	A6W7W5.
ModBase	Search...
Protein-protein interaction databases
STRING	A6W7W5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5335908.
GenomeReviews	Gene locus Krad_1416 in contig CP000750_GR.
KEGG	kra:Krad_1416.
NMPDR	fig|266940.1.peg.4559.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0264.
HOGENOM	HBG713289.
OMA	YLHGTRI.
Enzyme and pathway databases
BioCyc	KRAD266940:KRAD_1416-MONOMER.
Family and domain databases
HAMAP	MF_00050. EF_Ts. [Tree]
InterPro	IPR001816. Transl_elong_EFTs/EF1B. IPR014039. Transl_elong_EFTs/EF1B_dimer. IPR018101. Transl_elong_Ts_CS. IPR009060. UBA-like. IPR000449. UBA/transl_elong_EF1B_N. [Graphical view]
Gene3D	G3DSA:3.30.479.20. Transl_elong_EFTs/EF1B_dimer. 3 hits.
KO	K02357.
PANTHER	PTHR11741. Transl_elong_EFTs/EF1B. 1 hit.
Pfam	PF00889. EF_TS. 1 hit. PF00627. UBA. 1 hit. [Graphical view]
SUPFAM	SSF54713. EF_TS. 1 hit. SSF46934. UBA_like. 1 hit.
TIGRFAMs	TIGR00116. Tsf. 1 hit.
PROSITE	PS01126. EF_TS_1. 1 hit. PS01127. EF_TS_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFTS_KINRD

Accession

Primary (citable) accession number: A6W7W5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	August 21, 2007
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program