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A6W7S1 (A6W7S1_KINRD) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphopantetheine adenylyltransferase HAMAP MF_00151

EC=2.7.7.3 HAMAP MF_00151
Alternative name(s):
Dephospho-CoA pyrophosphorylase HAMAP MF_00151
Pantetheine-phosphate adenylyltransferase HAMAP MF_00151
Gene names
Name:coaD HAMAP MF_00151
Ordered Locus Names:Krad_1372
OrganismKineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) [Complete proteome] [HAMAP] EMBL ABS02860.1
Taxonomic identifier266940 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesKineosporiineaeKineosporiaceaeKineococcus

Protein attributes

Sequence length167 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate By similarity. HAMAP MF_00151

Catalytic activity

ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA. HAMAP MF_00151

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. HAMAP MF_00151

Subunit structure

Homohexamer By similarity. HAMAP MF_00151

Subcellular location

Cytoplasm By similarity HAMAP MF_00151.

Sequence similarities

Belongs to the bacterial CoaD family. HAMAP MF_00151

Sequences

Sequence LengthMass (Da)Tools
A6W7S1 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: D83D5D13594BA748

FASTA16717,435
        10         20         30         40         50         60 
MCPGSFDPVT LGHLDVLLRA AGMFDVVHVG VAVNPAKRGL LTGPERVGLV RAALEGSGDP 

        70         80         90        100        110        120 
RAERVVVEEF ADGLLVDHCR RLGAGVVVKG LRGGTDYAYE LPMALMNRHL AGVETVFLVG 

       130        140        150        160 
DPRFEHVSSS LVKEVARHGG DVSALVPPAV RAALVSRLGE NADAPGA 

« Hide

References

[1]"Complete sequence of chromosome of Kineococcus radiotolerans SRS30216."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., Bagwell C.E., Shimkets L., Berry C.J., Fliermans C., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-149 / DSM 14245 / SRS30216.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000750 Genomic DNA. Translation: ABS02860.1.
RefSeqYP_001361124.1. NC_009664.2.

3D structure databases

ProteinModelPortalA6W7S1.
SMRA6W7S1. Positions 2-158.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6W7S1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5335065.
GenomeReviewsGene locus Krad_1372 in contig CP000750_GR.
KEGGkra:Krad_1372.
NMPDRfig|266940.1.peg.1350.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0669.
HOGENOMHBG288308.
OMAAMSDFEY.

Family and domain databases

HAMAPMF_00151. PPAT_bact.
[Tree]
InterProIPR004821. Cyt_trans-rel.
IPR004820. Cytidylyltransf.
IPR001980. LPS_biosynth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KOK00954.
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR01510. CoaD_prev_kdtB. 1 hit.
TIGR00125. Cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA6W7S1_KINRD
AccessionPrimary (citable) accession number: A6W7S1
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: November 16, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)