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A6W7A8 (A6W7A8_KINRD) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
EC=2.5.1.19 HAMAP MF_00210
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP MF_00210
Gene names
Name:aroA HAMAP MF_00210
Ordered Locus Names:Krad_1209
OrganismKineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) [Complete proteome] [HAMAP] EMBL ABS02697.1
Taxonomic identifier266940 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Kineosporiineae › Kineosporiaceae › Kineococcus

Protein attributes

Sequence length449 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family. HAMAP MF_00210

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis HAMAP MF_00210
   Cellular componentCytoplasm HAMAP MF_00210
   Molecular functionTransferase HAMAP MF_00210 EMBL ABS02697.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A6W7A8 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 5D6FFB679AF622BE

FASTA44946,633
        10         20         30         40         50         60 
MTEDDPARTP GSAGPTDRLW AAPTAAGPLD AVVAVPGSKS LTNRYLVVAA LAERPSLLRG 

        70         80         90        100        110        120 
PLASRDTLLM VDALRLLGAD VAEGGRDAPG VDPADWVVRP GPVTGGARID CGLAGTVMRF 

       130        140        150        160        170        180 
LPPVAALAEE PVHFDGDDRA RERPMGAVLD GLRQLGALVD DGGRGLLPFS VQGPAGGLRG 

       190        200        210        220        230        240 
GPVRIDASAS SQFVSALLLV GARTREGLEL VHEGPPVPSE PHVRMTVEVL RDVGVVVDDS 

       250        260        270        280        290        300 
TPGRWFVEAG EINPLDVQVE PDLSNAGPFL AAAAVAGGRV RVPGWPQSTT QAGDLLRDVL 

       310        320        330        340        350        360 
DQMGAEVNLD REGLVVEGTG ELYGIDLDLH EAGELAPVIT ALAALASSPT RLRGIAHLRG 

       370        380        390        400        410        420 
HETDRLKALV TEVNALGGQA EETIDGLLVR PRPLHGGVFR TYADHRMATA GALLGLTVPG 

       430        440 
VLVEDVATTR KTLPDFPGMW ASMLAGTPA

« Hide

References

[1]"Complete sequence of chromosome of Kineococcus radiotolerans SRS30216."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., Bagwell C.E., Shimkets L., Berry C.J., Fliermans C., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-149 / DSM 14245 / SRS30216.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000750 Genomic DNA. Translation: ABS02697.1.
RefSeqYP_001360961.1. NC_009664.2.

3D structure databases

ProteinModelPortalA6W7A8.
SMRA6W7A8. Positions 18-444.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6W7A8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5337446.
GenomeReviewsGene locus Krad_1209 in contig CP000750_GR.
KEGGkra:Krad_1209.
NMPDRfig|266940.1.peg.2005.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0128.
HOGENOMHBG646626.
OMAHRMATAG.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA6W7A8_KINRD
AccessionPrimary (citable) accession number: A6W7A8
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: November 16, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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