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Protein

50S ribosomal protein L22

Gene

rplV

Organism
Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).UniRule annotation
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L22UniRule annotation
Gene namesi
Name:rplVUniRule annotation
Ordered Locus Names:Krad_0693
OrganismiKineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)
Taxonomic identifieri266940 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaKineosporialesKineosporiaceaeKineococcus
Proteomesi

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001422721 – 12650S ribosomal protein L22Add BLAST126

Proteomic databases

PRIDEiA6W5U3

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi266940.Krad_0693

Structurei

3D structure databases

ProteinModelPortaliA6W5U3
SMRiA6W5U3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL22 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105KAP Bacteria
COG0091 LUCA
HOGENOMiHOG000205046
KOiK02890
OMAiPQGRAHR
OrthoDBiPOG091H01RT

Family and domain databases

CDDicd00336 Ribosomal_L22, 1 hit
Gene3Di3.90.470.10, 1 hit
HAMAPiMF_01331_B Ribosomal_L22_B, 1 hit
InterProiView protein in InterPro
IPR001063 Ribosomal_L22
IPR018260 Ribosomal_L22/L17_CS
IPR036394 Ribosomal_L22/L17_sf
IPR005727 Ribosomal_L22_bac/chlpt-type
PANTHERiPTHR13501 PTHR13501, 1 hit
PfamiView protein in Pfam
PF00237 Ribosomal_L22, 1 hit
SUPFAMiSSF54843 SSF54843, 1 hit
TIGRFAMsiTIGR01044 rplV_bact, 1 hit
PROSITEiView protein in PROSITE
PS00464 RIBOSOMAL_L22, 1 hit

Sequencei

Sequence statusi: Complete.

A6W5U3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAKAQTRYL RVTPQKARRV VDLVRGKQAT EAVAVLSFAP QSAAEPVRKL
60 70 80 90 100
VESAMANAKF HADKHSEAFD PAEYVVKAIH VDEGPTMKRF RPRAQGRAGR
110 120
ILKRTSHITV VVAPAVKGAK KTRRTR
Length:126
Mass (Da):13,969
Last modified:August 21, 2007 - v1
Checksum:i2291CCD2A64F4431
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000750 Genomic DNA Translation: ABS02182.1
RefSeqiWP_012084976.1, NC_009664.2

Genome annotation databases

EnsemblBacteriaiABS02182; ABS02182; Krad_0693
KEGGikra:Krad_0693

Similar proteinsi

Entry informationi

Entry nameiRL22_KINRD
AccessioniPrimary (citable) accession number: A6W5U3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: August 21, 2007
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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