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A6W5C6 (A6W5C6_KINRD) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Inorganic pyrophosphatase HAMAP-Rule MF_00209
EC=3.6.1.1 HAMAP-Rule MF_00209
Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP-Rule MF_00209
Gene names
Name:ppa HAMAP-Rule MF_00209
Ordered Locus Names:Krad_0526 EMBL ABS02015.1
OrganismKineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) [Complete proteome] [HAMAP] EMBL ABS02015.1
Taxonomic identifier266940 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Kineosporiineae › Kineosporiaceae › Kineococcus ›

Protein attributes

Sequence length173 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP-Rule MF_00209

Cofactor

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP-Rule MF_00209

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00209.

Sequence similarities

Belongs to the PPase family. HAMAP-Rule MF_00209

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding561Magnesium 1 By similarity HAMAP-Rule MF_00209
Metal binding611Magnesium 1 By similarity HAMAP-Rule MF_00209
Metal binding611Magnesium 2 By similarity HAMAP-Rule MF_00209
Metal binding931Magnesium 1 By similarity HAMAP-Rule MF_00209

Sequences

Sequence LengthMass (Da)Tools
A6W5C6 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: DF6A0538EC9ACF85

FASTA17319,293
        10         20         30         40         50         60 
MSTPVVFDAT IEIPKGQRNK YEVDHETGRI RLDRMLFTST RYPHDYGFIE GTLGEDGDPL 

        70         80         90        100        110        120 
DVLVILEEPT FPGCLISCRA IGMFHMRDEA GGDDKVLAVP AGDPRWEKIQ DLGDISEFDR 

       130        140        150        160        170 
LEIQHFFETY KDLEPGKSVE GANWSGRAEA EKEIAASYER AAGTSYEAGA GHH

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References

[1]"Complete sequence of chromosome of Kineococcus radiotolerans SRS30216."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., Bagwell C.E., Shimkets L., Berry C.J., Fliermans C., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-149 / DSM 14245 / SRS30216.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000750 Genomic DNA. Translation: ABS02015.1.
RefSeqYP_001360279.1. NC_009664.2.

3D structure databases

ProteinModelPortalA6W5C6.
SMRA6W5C6. Positions 5-160.
ModBaseSearch...

Protein-protein interaction databases

STRING266940.Krad_0526.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS02015; ABS02015; Krad_0526.
GeneID5336016.
KEGGkra:Krad_0526.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0221.
HOGENOMHOG000236473.
KOK01507.
OMAMFRMRDE.

Enzyme and pathway databases

BioCycKRAD266940:GI4N-1713-MONOMER.

Family and domain databases

Gene3D3.90.80.10. 1 hit.
HAMAPMF_00209. Inorganic_PPase.
InterProIPR008162. Pyrophosphatase.
[Graphical view]
PANTHERPTHR10286. PTHR10286. 1 hit.
PfamPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMSSF50324. Pyrophosphatase. 1 hit.
PROSITEPS00387. PPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA6W5C6_KINRD
AccessionPrimary (citable) accession number: A6W5C6
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: May 29, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info