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A6W2P8 (A6W2P8_MARMS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Choline dehydrogenase HAMAP MF_00750
Short name=CDH HAMAP MF_00750
Short name=CHD HAMAP MF_00750
EC=1.1.99.1 HAMAP MF_00750
Gene names
Name:betA HAMAP MF_00750
Ordered Locus Names:Mmwyl1_4081
OrganismMarinomonas sp. (strain MWYL1) [Complete proteome] [HAMAP] EMBL ABR72977.1
Taxonomic identifier400668 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Marinomonas

Protein attributes

Sequence length560 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. HAMAP MF_00750 SAAS SAAS007867

Catalytic activity

Choline + acceptor = betaine aldehyde + reduced acceptor. HAMAP MF_00750 SAAS SAAS007867

Cofactor

FAD By similarity. HAMAP MF_00750 SAAS SAAS007867

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. HAMAP MF_00750 SAAS SAAS007867

Sequence similarities

Belongs to the GMC oxidoreductase family. HAMAP MF_00750

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding7 – 3630FAD By similarity HAMAP MF_00750

Sites

Active site4761 By similarity HAMAP MF_00750

Sequences

Sequence LengthMass (Da)Tools
A6W2P8 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: C516BE895F5716E8

FASTA56061,891
        10         20         30         40         50         60 
MANETYDYII VGAGSAGCVL ADRLTESGEH KVLLLEMGGS DKSVFIQMPT ALSYPMNTNK 

        70         80         90        100        110        120 
YAWQFHTEKE PGLDGREMHC PRGKVLGGSS SINGMVYVRG HACDFDQWEE NGAKGWNYQS 

       130        140        150        160        170        180 
CLPYFKKAET WKGGADLYRG GNGPLSTNNG NDMTYNPLYQ AFIDAGEEAG YGKTEDYNGF 

       190        200        210        220        230        240 
RQEGFGPMHM TVKNGVRAST ANAYLRRAMK RPNLTLKTGV LSHKVLFANG KANGKTATGI 

       250        260        270        280        290        300 
EFSKNGQTQQ ANASKEVILS AGSVGSPQLL QLSGVGPKDV LEKAGVPVVH ELPGVGENLQ 

       310        320        330        340        350        360 
DHLEVYFQYY CKQPVTLNSK LGLISKGLIG TRWMLFKTGL GATNHFESCG FIRSRSGLKW 

       370        380        390        400        410        420 
PNIQYHFLPA AMRYDGQAAV KGHGFQVHVG PNKPESRGKL WIESANPAAK PRILFNYIST 

       430        440        450        460        470        480 
EQDKQDWRDT IRLTREVLQQ SALNEYRGDE IQPGMNIQSD EEIDQWVREN VESAYHPSCT 

       490        500        510        520        530        540 
CKMGDDKDPM AVLNEQCQVR GIENLRVVDS SIFPTITNGN LNAPTIMVAE KAADMILGKD 

       550        560 
TLPSLNAPVW IHPEFETKQR

« Hide

References

[1]"Complete sequence of Marinomonas sp. MWYL1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Johnston A.W.B., Todd J.D., Rogers R., Wexler M., Bond P.L., Li Y., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MWYL1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000749 Genomic DNA. Translation: ABR72977.1.
RefSeqYP_001342912.1. NC_009654.1.

3D structure databases

ProteinModelPortalA6W2P8.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6W2P8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5366906.
GenomeReviewsGene locus Mmwyl1_4081 in contig CP000749_GR.
KEGGmmw:Mmwyl1_4081.
PATRIC22471825. VBIMarSp124341_4230.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2303.
HOGENOMHBG734713.
OMAHMTVKNG.
ProtClustDBPRK02106.

Family and domain databases

HAMAPMF_00750. Choline_dehydrogen.
[Tree]
InterProIPR011533. Choline_dehydrogenase.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
KOK00108.
PfamPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFPIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsTIGR01810. BetA. 1 hit.
PROSITEPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA6W2P8_MARMS
AccessionPrimary (citable) accession number: A6W2P8
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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