A6W239 (A6W239_MARMS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 2 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 2 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 2 HAMAP MF_01401

Gene names

Name:	msrA2 HAMAP MF_01401
Ordered Locus Names:	Mmwyl1_3869

Organism

Marinomonas sp. (strain MWYL1) [Complete proteome] [HAMAP] EMBL ABR72768.1

Taxonomic identifier

400668 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Marinomonas

Protein attributes

Sequence length	208 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Domain	Signal EMBL ABR72768.1
Molecular function	Oxidoreductase HAMAP MF_01401 EMBL ABR72768.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 29	29	Potential EMBL ABR72768.1
	Chain	30 – 208	179	Potential EMBL ABR72768.1		PRO_5000259715
Sites
	Active site	39	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	A6W239 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 474404D2C8712BB9	FASTA	208	23,447
	10 20 30 40 50 60 MNVKHIFNST LGMLLLTGVT TFSSVSQAAP QTMIVAGGCF WCVESDFELV QGVSDVVSGY 70 80 90 100 110 120 TGGHTENPTY SLVSAKNTGH FEAVIIYFDD DIVSLKTLAD YYWKTIDPTD AKGQFCDKGS 130 140 150 160 170 180 PYKTAMFYQD DQQKAVFEAS LAKVKKTKPF EEDIVTEILP AKKFYPAEEY HQSYYTKNPI 190 200 RYAFYRASCG RDNRIESLWG EVASHQYH

References

[1]

"Complete sequence of Marinomonas sp. MWYL1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Johnston A.W.B., Todd J.D., Rogers R., Wexler M., Bond P.L., Li Y., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MWYL1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000749 Genomic DNA. Translation: ABR72768.1.
RefSeq	YP_001342703.1. NC_009654.1.
3D structure databases
ProteinModelPortal	A6W239.
ModBase	Search...
Protein-protein interaction databases
STRING	A6W239.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5368932.
GenomeReviews	Gene locus Mmwyl1_3869 in contig CP000749_GR.
KEGG	mmw:Mmwyl1_3869.
PATRIC	22471361. VBIMarSp124341_4003.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
HOGENOM	HBG748152.
OMA	KIEYDVA.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6W239_MARMS

Accession

Primary (citable) accession number: A6W239

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)