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A6W1W5

- GLSA_MARMS

UniProt

A6W1W5 - GLSA_MARMS

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Protein

Glutaminase

Gene

glsA

Organism
Marinomonas sp. (strain MWYL1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei61 – 611SubstrateUniRule annotation
Binding sitei111 – 1111SubstrateUniRule annotation
Binding sitei155 – 1551SubstrateUniRule annotation
Binding sitei162 – 1621SubstrateUniRule annotation
Binding sitei186 – 1861SubstrateUniRule annotation
Binding sitei238 – 2381SubstrateUniRule annotation
Binding sitei256 – 2561Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciMSP400668:GHKD-3886-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:Mmwyl1_3795
OrganismiMarinomonas sp. (strain MWYL1)
Taxonomic identifieri400668 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesMarinomonas
ProteomesiUP000001113: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303GlutaminasePRO_1000079077Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi400668.Mmwyl1_3795.

Structurei

3D structure databases

ProteinModelPortaliA6W1W5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A6W1W5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEDLLHSIEQ KVKPLIGLGK VADYIPALAN VDPNQFGIAI YSNNGELYHA
60 70 80 90 100
GQAYTDFSIQ SISKVFSLTL AIKHYGEDMW KRVGREPSGN PFNSLVQLEY
110 120 130 140 150
EAGVPRNPFI NAGALVISDM NQSRFASPHY AMREFIRRLA DNPHLNSDQI
160 170 180 190 200
VANSEYEFRA RNASMAYLMK AFGNFENDVE DVLHSYFDNC AMRMNCVDLA
210 220 230 240 250
KSFSFLANKG YSQLSGEQIL SARETTQVNG LLATSGLYDE AGNFAYRVGL
260 270 280 290 300
PGKSGVGGGI IAIVPNRFSV CVWSPELNKS GNSLAGMAAL EALSESIGWS

VFG
Length:303
Mass (Da):33,206
Last modified:August 21, 2007 - v1
Checksum:iC41F6BFE4584436C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000749 Genomic DNA. Translation: ABR72694.1.
RefSeqiWP_012071459.1. NC_009654.1.
YP_001342629.1. NC_009654.1.

Genome annotation databases

EnsemblBacteriaiABR72694; ABR72694; Mmwyl1_3795.
GeneIDi5368859.
KEGGimmw:Mmwyl1_3795.
PATRICi22471213. VBIMarSp124341_3929.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000749 Genomic DNA. Translation: ABR72694.1 .
RefSeqi WP_012071459.1. NC_009654.1.
YP_001342629.1. NC_009654.1.

3D structure databases

ProteinModelPortali A6W1W5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 400668.Mmwyl1_3795.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR72694 ; ABR72694 ; Mmwyl1_3795 .
GeneIDi 5368859.
KEGGi mmw:Mmwyl1_3795.
PATRICi 22471213. VBIMarSp124341_3929.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci MSP400668:GHKD-3886-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MWYL1.

Entry informationi

Entry nameiGLSA_MARMS
AccessioniPrimary (citable) accession number: A6W1W5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 21, 2007
Last modified: October 1, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3