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A6VZM0 (A6VZM0_MARMS) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylamine--glycine ligase HAMAP-Rule MF_00138
EC=6.3.4.13 HAMAP-Rule MF_00138
Alternative name(s):
GARS HAMAP-Rule MF_00138
Glycinamide ribonucleotide synthetase HAMAP-Rule MF_00138
Phosphoribosylglycinamide synthetase HAMAP-Rule MF_00138
Gene names
Name:purD HAMAP-Rule MF_00138
Ordered Locus Names:Mmwyl1_2988
OrganismMarinomonas sp. (strain MWYL1) [Complete proteome] [HAMAP] EMBL ABR71899.1
Taxonomic identifier400668 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Marinomonas

Protein attributes

Sequence length428 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide. HAMAP-Rule MF_00138

Cofactor

Binds (magnesium or manganese,ion) per subunit By similarity. HAMAP-Rule MF_00138

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2. HAMAP-Rule MF_00138

Sequence similarities

Belongs to the GARS family. HAMAP-Rule MF_00138

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00138

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain109 – 316208ATP-grasp By similarity HAMAP-Rule MF_00138
Nucleotide binding135 – 19662ATP By similarity HAMAP-Rule MF_00138

Sites

Metal binding2861Magnesium or manganese By similarity HAMAP-Rule MF_00138
Metal binding2881Magnesium or manganese By similarity HAMAP-Rule MF_00138

Sequences

Sequence LengthMass (Da)Tools
A6VZM0 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: BBDBE817C5B62C3C

FASTA42845,179
        10         20         30         40         50         60 
MKVLIIGNGG REHALAWKTA ESNQVEKVFV APGNAGSATE NKVENVNIGV TDIADLVAFA 

        70         80         90        100        110        120 
KKENIDLTIV GPEAPLVIGV VDAFEKEGLA IFGPTAAAAQ LEGSKAFTKD FLARHNIPTA 

       130        140        150        160        170        180 
AYGNFTEIEP AVAYIKQHGA PIVVKADGLA AGKGVILAQT EAEAIEAVED MLQGNSFGDA 

       190        200        210        220        230        240 
GSRVVIEEFL VGEEASFICM VDGETVLPMA TSQDHKARDN GDKGPNTGGM GAYSPAPVVT 

       250        260        270        280        290        300 
PEIHDRIMNE VIMPTVKGMN AEGNRYRGFL YAGVMIAPDG TPKTLEYNCR FGDPETQPIM 

       310        320        330        340        350        360 
MRLRSDLAQM CLAAVNGKLD TVEADWDPRA SLGVVLAAGG YPADYAKGDV ISGLDTNLPE 

       370        380        390        400        410        420 
GQKVFQAGTA LKDGQVVTNG GRVLCAVALG NTVAEAQAAA YDVVNTLSWD KVYFRTDIGH 


RAIAREQK

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References

[1]"Complete sequence of Marinomonas sp. MWYL1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Johnston A.W.B., Todd J.D., Rogers R., Wexler M., Bond P.L., Li Y., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MWYL1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000749 Genomic DNA. Translation: ABR71899.1.
RefSeqYP_001341834.1. NC_009654.1.

3D structure databases

ProteinModelPortalA6VZM0.
SMRA6VZM0. Positions 1-425.
ModBaseSearch...

Protein-protein interaction databases

STRING400668.Mmwyl1_2988.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR71899; ABR71899; Mmwyl1_2988.
GeneID5364909.
KEGGmmw:Mmwyl1_2988.
PATRIC22469481. VBIMarSp124341_3092.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0151.
HOGENOMHOG000033463.
KOK01945.
OMAMGAYTPL.

Enzyme and pathway databases

BioCycMSP400668:GHKD-3099-MONOMER.
UniPathwayUPA00074; UER00125.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
3.90.600.10. 1 hit.
HAMAPMF_00138. GARS.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR016185. PreATP-grasp_dom.
IPR020561. PRibGlycinamid_synth_ATP-grasp.
IPR000115. PRibGlycinamide_synth.
IPR020560. PRibGlycinamide_synth_C-dom.
IPR020559. PRibGlycinamide_synth_CS.
IPR020562. PRibGlycinamide_synth_N.
IPR011054. Rudment_hybrid_motif.
[Graphical view]
PfamPF01071. GARS_A. 1 hit.
PF02843. GARS_C. 1 hit.
PF02844. GARS_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
SSF51246. Rudmnt_hyb_motif. 1 hit.
TIGRFAMsTIGR00877. purD. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00184. GARS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA6VZM0_MARMS
AccessionPrimary (citable) accession number: A6VZM0
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info