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A6VZ12 (UXUA_MARMS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannonate dehydratase
EC=4.2.1.8
Alternative name(s):
D-mannonate hydrolase
Gene names
Name:uxuA
Ordered Locus Names:Mmwyl1_2778
OrganismMarinomonas sp. (strain MWYL1) [Complete proteome] [HAMAP]
Taxonomic identifier400668 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Marinomonas

Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106

Sequence similarities

Belongs to the mannonate dehydratase family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionmannonate dehydratase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 391391Mannonate dehydratase HAMAP MF_00106
PRO_1000075902

Sequences

Sequence LengthMass (Da)Tools
A6VZ12 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 54FF68FF2EED826E

FASTA39144,006
        10         20         30         40         50         60 
MEHTWRWFGP NDETTLTDIR QTGATGVVTA LHEIPNGEVW PVEAIKARKA MIEAHTLRWS 

        70         80         90        100        110        120 
VVESVPVHED IKKRTGNYQE YIQNYKQTLL NLAECGIDTV CYNFMPVLDW TRTDLDYELP 

       130        140        150        160        170        180 
DGSRALRFDQ TAFAAFELYI LERKGAESEY SDEEKAQAKI FLENLKAEDK DRLVANIIAG 

       190        200        210        220        230        240 
LPGSEESYTI EQFREKLDEY AGIDKDKLRE HLKLFLEEIV PAAEQGGLRL AIHPDDPPRP 

       250        260        270        280        290        300 
ILGLPRVVSV KDDIEWLLGA VPSPVNGITL CTGSYGVRAD NDLVDMVQRF GSNIFFTHLR 

       310        320        330        340        350        360 
STKREEVAGS FHEASHLGGD VDMVGVVRAL LVEEKKRNDN NAPSLIPMRP DHGHQILNDL 

       370        380        390 
EKNSKPGYSK LGRMKGLAEV RGLELGLKST L

« Hide

References

[1]"Complete sequence of Marinomonas sp. MWYL1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Johnston A.W.B., Todd J.D., Rogers R., Wexler M., Bond P.L., Li Y., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MWYL1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000749 Genomic DNA. Translation: ABR71691.1.
RefSeqYP_001341626.1. NC_009654.1.

3D structure databases

ProteinModelPortalA6VZ12.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6VZ12.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5368020.
GenomeReviewsGene locus Mmwyl1_2778 in contig CP000749_GR.
KEGGmmw:Mmwyl1_2778.
PATRIC22469051. VBIMarSp124341_2877.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1312.
HOGENOMHBG585927.
OMAVHEEIKT.
ProtClustDBPRK03906.

Enzyme and pathway databases

BioCycMSP400668:MMWYL1_2778-MONOMER.

Family and domain databases

HAMAPMF_00106. UxuA.
[Tree]
InterProIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01686.
PfamPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFPIRSF016049. Man_dehyd. 1 hit.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR00695. UxuA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUXUA_MARMS
AccessionPrimary (citable) accession number: A6VZ12
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 21, 2007
Last modified: January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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