A6VWY4 (TRPF_MARMS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	Mmwyl1_2041

Organism

Marinomonas sp. (strain MWYL1) [Complete proteome] [HAMAP]

Taxonomic identifier

400668 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Oceanospirillaceae › Marinomonas

Protein attributes

Sequence length	205 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 205	205	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_1000197110

Sequences

	Sequence		Length	Mass (Da)
	A6VWY4 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 699E2FF2A24D15D4	FASTA	205	21,849
	10 20 30 40 50 60 MNCRVKICGI TNLDDAMVAC RYGADALGFV FYEKSPRYVA PDMANAIVAQ LPPFIIPVAL 70 80 90 100 110 120 FVDADTSLVN SVISGSSRWT IQFHGSESES ECISYQRPYI KALRIQRGDD VAALVDQYPS 130 140 150 160 170 180 ASAMLLDAYK AGVPGGTGEV FDWSLIPIGL SKPIVLAGGL TPSNVKQAIK QVKPYAVDVS 190 200 GGVELSKGIK SEPLVQEFIS GAKCG

References

[1]

"Complete sequence of Marinomonas sp. MWYL1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Johnston A.W.B., Todd J.D., Rogers R., Wexler M., Bond P.L., Li Y., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MWYL1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000749 Genomic DNA. Translation: ABR70963.1.
RefSeq	YP_001340898.1. NC_009654.1.
3D structure databases
ProteinModelPortal	A6VWY4.
ModBase	Search...
Protein-protein interaction databases
STRING	400668.Mmwyl1_2041.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABR70963; ABR70963; Mmwyl1_2041.
GeneID	5367064.
KEGG	mmw:Mmwyl1_2041.
PATRIC	22467451. VBIMarSp124341_2113.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0135.
HOGENOM	HOG000161598.
KO	K01817.
OMA	KTHDWAV.
Enzyme and pathway databases
BioCyc	MSP400668:GHKD-2152-MONOMER.
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_MARMS

Accession

Primary (citable) accession number: A6VWY4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	August 21, 2007
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program