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A6VWF0 (A6VWF0_MARMS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA 1 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 1 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 1 HAMAP MF_01401
Gene names
Name:msrA1 HAMAP MF_01401
Ordered Locus Names:Mmwyl1_1855
OrganismMarinomonas sp. (strain MWYL1) [Complete proteome] [HAMAP] EMBL ABR70779.1
Taxonomic identifier400668 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Marinomonas

Protein attributes

Sequence length219 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
   Molecular functionOxidoreductase HAMAP MF_01401 EMBL ABR70779.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processprotein modification process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionpeptide-methionine-(S)-S-oxide reductase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site581 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
A6VWF0 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: E421ABA567273454

FASTA21923,761
        10         20         30         40         50         60 
MPSNIEAILK KSAIPAEADA LPGRSTPLKI SGIHAVNNEP FVRSEKPNES EIILGMGCFW 

        70         80         90        100        110        120 
GAERKLWNTP GVIVTSVGYA GGFTSNPTYE EVCSGQTGHS EVVQVVFDTS IISLEGVLKV 

       130        140        150        160        170        180 
FWENHDPTQG MRQGNDIGSQ YRSVIYTTND KDMAIVEASK AAFQKELISA GHGMITTEIE 

       190        200        210 
PLDTYYFAEE YHQQYLHKNP NGYCGLAGTG VSCPIGLAV

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References

[1]"Complete sequence of Marinomonas sp. MWYL1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Johnston A.W.B., Todd J.D., Rogers R., Wexler M., Bond P.L., Li Y., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MWYL1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000749 Genomic DNA. Translation: ABR70779.1.
RefSeqYP_001340714.1. NC_009654.1.

3D structure databases

ProteinModelPortalA6VWF0.
SMRA6VWF0. Positions 16-214.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6VWF0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5369054.
GenomeReviewsGene locus Mmwyl1_1855 in contig CP000749_GR.
KEGGmmw:Mmwyl1_1855.
PATRIC22467051. VBIMarSp124341_1919.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0225.
HOGENOMHBG748152.
OMAQETSFEQ.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA6VWF0_MARMS
AccessionPrimary (citable) accession number: A6VWF0
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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