A6VRD3 (A6VRD3_MARMS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Shikimate dehydrogenase 2 HAMAP MF_00222
EC=1.1.1.25 HAMAP MF_00222

Gene names

Name:	aroE2 HAMAP MF_00222
Ordered Locus Names:	Mmwyl1_0070

Organism

Marinomonas sp. (strain MWYL1) [Complete proteome] [HAMAP] EMBL ABR69012.1

Taxonomic identifier

400668 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Marinomonas

Protein attributes

Sequence length	296 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222
Sequence similarities	Belongs to the shikimate dehydrogenase family. HAMAP MF_00222

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00222
Ligand	NADP HAMAP MF_00222
Molecular function	Oxidoreductase HAMAP MF_00222 EMBL ABR69012.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	130 – 134	5	NADP By similarity HAMAP MF_00222
Sites
	Active site	71	1	Proton acceptor By similarity HAMAP MF_00222

Sequences

	Sequence		Length	Mass (Da)
	A6VRD3 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 9839B96AFDDA2A9D	FASTA	296	31,930
	10 20 30 40 50 60 MSKNFLSELT GSFATPALEN PTGVMMEAAY RDLGLDWRYI NCEIQPDDLK NAVLGARAMN 70 80 90 100 110 120 WRGFNCSIPH KVSVISHLDD LGESARIIGA VNTVVNRDGK LIGENTDGRG FVESVKSSLE 130 140 150 160 170 180 LTKTRVVLFG AGGAARAVAV ELALAGVAHI TIVNRNQKRG EELAKLVADN TSAGAEYHAW 190 200 210 220 230 240 TKQYQIPADT DLVINVTSIG LFPDVEVELD IDTESIKSSM VVADGIFNPP ATRLIQTAKT 250 260 270 280 290 KGCTTVNGLG MLVQQGVITF EYWTGKTPSI EVMKAALRDA LDITDLDSTD LESTEK

References

[1]

"Complete sequence of Marinomonas sp. MWYL1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Johnston A.W.B., Todd J.D., Rogers R., Wexler M., Bond P.L., Li Y., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MWYL1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000749 Genomic DNA. Translation: ABR69012.1.
RefSeq	YP_001338947.1. NC_009654.1.
3D structure databases
ProteinModelPortal	A6VRD3.
ModBase	Search...
Protein-protein interaction databases
STRING	A6VRD3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5368530.
GenomeReviews	Gene locus Mmwyl1_0070 in contig CP000749_GR.
KEGG	mmw:Mmwyl1_0070.
PATRIC	22463329. VBIMarSp124341_0074.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0169.
HOGENOM	HBG553408.
OMA	AFRVENE.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR011342. Shikimate_DH. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. IPR006151. Shikm_DH/Glu-tRNA_Rdtase. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00014.
Pfam	PF01488. Shikimate_DH. 1 hit. PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00507. AroE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6VRD3_MARMS

Accession

Primary (citable) accession number: A6VRD3

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)