Reviewed, UniProtKB/Swiss-Prot A6VQ84 (SYK3_ACTSZ)

Names and origin

Protein names

Recommended name:
    Putative lysyl-tRNA synthetase
    EC=6.1.1.6
Alternative name(s):
    Lysine--tRNA ligase
      Short name=LysRS
    GX

Gene names

Name:	poxA
Ordered Locus Names:	Asuc_1779

Organism

Actinobacillus succinogenes (strain ATCC 55618 / 130Z) [Complete proteome] [HAMAP]

Taxonomic identifier

339671 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length	323 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Could be a lysyl-tRNA synthetase. HAMAP MF_00174
Catalytic activity	ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP MF_00174
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP lysine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 323	323	Putative lysyl-tRNA synthetase HAMAP MF_00174		PRO_1000071618

Sequences

	Sequence		Length	Mass (Da)
	A6VQ84-1 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 513EEBDBF495ED03	FASTA	323	37,302
	10 20 30 40 50 60 MFEQEQWQPT ANVETLFARA KIINNIRRFF TDRGVLEVET PILSEFGVTD VHLSTFSTEF 70 80 90 100 110 120 VAPQAERSKT LWLNTSPEYH MKRLLAAGTG AIFQLCHVFR NEEAGSRHNP EFTMLEWYRP 130 140 150 160 170 180 HFDMYRLINE VDDLLQQILD CEPAESMSYQ FAFQEFVGVD PLSAERPILV ELARKYNFMC 190 200 210 220 230 240 DLDEDRDTLL QFLFSTVVEP KIGQERPVAV YHFPATQAAL AQISSEDHRV AERFEFYYKG 250 260 270 280 290 300 LELANGFHEL TDHREQLHRF EQDNVQRAKL ALPQREIDRR LLGALQAGVP NTSGVALGVD 310 320 RLVMIALDKK RIEEVMAFAI NNA

References

[1]

"Complete sequence of Actinobacillus succinogenes 130Z." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Vieille C., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000746 Genomic DNA. Translation: ABR75131.1.
RefSeq	YP_001345066.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A6VQ84.
Genome annotation databases
GeneID	5348419.
GenomeReviews	Gene locus Asuc_1779 in contig CP000746_GR.
KEGG	asu:Asuc_1779.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	VFRNEEA.
Family and domain databases
HAMAP	MF_00174. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-reg. IPR004525. Lys-tRNA-synth-rel. IPR018149. Lys-tRNA-synth_II_C. [Graphical view]
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. [Graphical view]
PRINTS	PR00982. TRNASYNTHLYS.
TIGRFAMs	TIGR00462. genX. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYK3_ACTSZ

Accession

Primary (citable) accession number: A6VQ84

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	August 21, 2007
Last modified:	November 3, 2009
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)