Reviewed, UniProtKB/Swiss-Prot A6VP84 (GLMM_ACTSZ)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Asuc_1422

Organism

Actinobacillus succinogenes (strain ATCC 55618 / 130Z) [Complete proteome] [HAMAP]

Taxonomic identifier

339671 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length	444 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 444	444	Phosphoglucosamine mutase HAMAP MF_01554		PRO_1000073568
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A6VP84-1 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 5D557141BF9406D8	FASTA	444	47,437
	10 20 30 40 50 60 MAERKYFGTD GVRGKVGSFP ITPDFALKLG WAAGKVLATH GSKKVLIGKD TRISGYMLES 70 80 90 100 110 120 ALEAGLTAAG LSAVFVGPMP TPAVAYLTRT FRAEAGVVIS ASHNPYDDNG IKFFSAEGTK 130 140 150 160 170 180 LPDDVEEAIE ALLEQPMDCV ESAELGKASR INDAAGRYIE FCKSTFPTSL SLEGYKIVVD 190 200 210 220 230 240 CAHGATYHIA PSVLRELGAE IIEIGTKPNG LNINEKCGAT DIEALRHKVL EIGADVGLAY 250 260 270 280 290 300 DGDGDRIMMV DHLGNKVDGD QILYIIARET LRAGHLKGGV VGTLMSNMSL EIALKQLGIP 310 320 330 340 350 360 FLRANVGDRY VLEKMQENGW KLGGENSGHI IILDKNTTGD GIIASLAVLT AMAQHKLSLH 370 380 390 400 410 420 ELTGAVKLFP QVLINVRFAG GENPLNSEKV KAVAAEVEQR LAGKGRILLR KSGTEPLIRV 430 440 MVECEDAVLA QKSAEEIAEA VKNS

References

[1]

"Complete sequence of Actinobacillus succinogenes 130Z." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Vieille C., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000746 Genomic DNA. Translation: ABR74781.1.
RefSeq	YP_001344716.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A6VP84.
Genome annotation databases
GeneID	5349178.
GenomeReviews	Gene locus Asuc_1422 in contig CP000746_GR.
KEGG	asu:Asuc_1422.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	VHDRYIE.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_ACTSZ

Accession

Primary (citable) accession number: A6VP84

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	August 21, 2007
Last modified:	November 3, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)