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Protein

Glycogen synthase

Gene

glgA

Organism
Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciASUC339671:GHDX-1422-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:Asuc_1355
OrganismiActinobacillus succinogenes (strain ATCC 55618 / 130Z)
Taxonomic identifieri339671 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
ProteomesiUP000001114: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 476476Glycogen synthasePRO_1000072413Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi339671.Asuc_1355.

Structurei

3D structure databases

ProteinModelPortaliA6VP18.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294941.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

A6VP18-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKVLHVCSEF YPLLKTGGLA DVVGALPAAQ KAIGDDARIL IPAYPAIWRG
60 70 80 90 100
IPDTVVVAEF DNFAGHVTLR YGIYNGVGVY LIDAPHLYAR EGNPYHDQWY
110 120 130 140 150
NDYADNYKRF GLLGWVASEL ALGLDFWWQA EVVHAHDWHA GLASAYLAAK
160 170 180 190 200
GHPAKSVFTI HNLAYQGKFA ARHLIELGLP VDMFNVNGLE LYGEISYLKA
210 220 230 240 250
GLFYSDMVTT VSPTYAKEIT TTEFGYGLQG LLSTLDQQNR LAGVLNGVDD
260 270 280 290 300
SIWHPNNDPY IHHHYKLKSM SGKAKNKALL QERFNLPQNP NVPVFVMITR
310 320 330 340 350
LTEQKGVDLL LQCADEIVNQ GGQLMILGSG APHLQDWVNW LASQHPDNVG
360 370 380 390 400
VWIGYDEPLS HLMVAGGDVI LVPSRFEPCG LTQLYGLKYG TLPLVRKTGG
410 420 430 440 450
LADTVVDSSA ENIKARRATG FVFNNAEPEA LRHCIQRVFS LWSKQRTWFT
460 470
VRTVAMEQDF GWRVAAHRYH ELYNKI
Length:476
Mass (Da):53,165
Last modified:August 21, 2007 - v1
Checksum:i278B6F7697860790
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000746 Genomic DNA. Translation: ABR74715.1.
RefSeqiWP_012073092.1. NC_009655.1.
YP_001344650.1. NC_009655.1.

Genome annotation databases

EnsemblBacteriaiABR74715; ABR74715; Asuc_1355.
GeneIDi5347963.
KEGGiasu:Asuc_1355.
PATRICi20761082. VBIActSuc117883_1418.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000746 Genomic DNA. Translation: ABR74715.1.
RefSeqiWP_012073092.1. NC_009655.1.
YP_001344650.1. NC_009655.1.

3D structure databases

ProteinModelPortaliA6VP18.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi339671.Asuc_1355.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR74715; ABR74715; Asuc_1355.
GeneIDi5347963.
KEGGiasu:Asuc_1355.
PATRICi20761082. VBIActSuc117883_1418.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294941.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciASUC339671:GHDX-1422-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production."
    McKinlay J.B., Laivenieks M., Schindler B.D., McKinlay A.A., Siddaramappa S., Challacombe J.F., Lowry S.R., Clum A., Lapidus A.L., Burkhart K.B., Harkins V., Vieille C.
    BMC Genomics 11:680-680(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 55618 / 130Z.

Entry informationi

Entry nameiGLGA_ACTSZ
AccessioniPrimary (citable) accession number: A6VP18
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: August 21, 2007
Last modified: January 7, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.