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A6VP15 (GLGB_ACTSZ) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:Asuc_1352
OrganismActinobacillus succinogenes (strain ATCC 55618 / 130Z) [Complete proteome] [HAMAP]
Taxonomic identifier339671 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus

Protein attributes

Sequence length829 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 8298291,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_1000072735

Sites

Active site4051Nucleophile By similarity
Active site4581Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
A6VP15 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 5BE0A3BD25EFE7A5

FASTA82994,021
        10         20         30         40         50         60 
MTTFVTQDTI NAFFDGRHAD PFAVLGMHET DNGIEIRALL PDAGRVVVID KETQDEVCEL 

        70         80         90        100        110        120 
SRIDERGFFA GIMPQRNSFF NYQLQVSWGN EVLRIEDPYR FHPMIQELDN WLLAEGSHLR 

       130        140        150        160        170        180 
PYEVLGAHFM ECDHVSGVNF RLWAPNAKRV SVVGDFNYWD GRRHPMRFHQ ASGVWELFIP 

       190        200        210        220        230        240 
KVALGDLYKF ELLDNNNRLR LKSDPYAFAA QLRPDTASQI SVLPEIQEMT AARRKANQLD 

       250        260        270        280        290        300 
QPISIYEVHL GSWRRNLANN FWLNYDEIAD ELIPYVKEMG FTHIELLPIS EFPFDGSWGY 

       310        320        330        340        350        360 
QPIGLYAPTS RFGSPEGFKR FVDKAHAAGI NVILDWVPGH FPSDTHGLAT FDGTALYEHA 

       370        380        390        400        410        420 
DPKEGYHQDW NTLIYNYGRH EVKNYLSGNA LYWVERFGLD GIRVDAVASM IYRDYSRRDG 

       430        440        450        460        470        480 
EWIPNQYGGR ENLEAIEFLK HTNYILGTEH PGVMCVAEES TAFAGVTLPP ENGGLGFNFK 

       490        500        510        520        530        540 
WNMGWMNDTL SYMKLDPIYR QYNHSKLTFG MLYQYSENFV LPLSHDEVVH GKCSLLDKMP 

       550        560        570        580        590        600 
GDTWQKFANL RAYYGYMWAY PGKKLLFMGN EFAQGREWNY QESLDWYLLD EFHGGGWHSG 

       610        620        630        640        650        660 
VQRLVKDLNK TYQKQSALYQ LDTKPEGFEW LVVDDAQNSV FVFERRNAKG EPLIVVSNFT 

       670        680        690        700        710        720 
PVPRENYRFG VNVAGSYEEI LNTDADIYKG SGLNNGGVID SEEIESHGKT QSISITVPPL 

       730        740        750        760        770        780 
ATVYFKLKSA RKVASPRKVT KKKTTADGAE ATAKNASASK ATKVSTKKTV KSSEAKPVKA 

       790        800        810        820 
ATKSSVTKVA TKKSTDKPTA KATRTKKATV TKTAKASAKT TAKKTKDNA 

« Hide

References

[1]"Complete sequence of Actinobacillus succinogenes 130Z."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Vieille C., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 55618 / 130Z.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000746 Genomic DNA. Translation: ABR74712.1.
RefSeqYP_001344647.1. NC_009655.1.

3D structure databases

ProteinModelPortalA6VP15.
SMRA6VP15. Positions 117-725.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING339671.Asuc_1352.

Protein family/group databases

CAZyCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR74712; ABR74712; Asuc_1352.
GeneID5349403.
KEGGasu:Asuc_1352.
PATRIC20761076. VBIActSuc117883_1415.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMARSISKRI.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycASUC339671:GHDX-1419-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_ACTSZ
AccessionPrimary (citable) accession number: A6VP15
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: August 21, 2007
Last modified: June 11, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries