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A6VP11 (SYQ_ACTSZ) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:Asuc_1348
OrganismActinobacillus succinogenes (strain ATCC 55618 / 130Z) [Complete proteome] [HAMAP]
Taxonomic identifier339671 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus

Protein attributes

Sequence length559 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 559559Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_1000095475

Regions

Motif44 – 5411"HIGH" region HAMAP-Rule MF_00126
Motif279 – 2835"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site2821ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
A6VP11 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: E8377817F028EE04

FASTA55964,366
        10         20         30         40         50         60 
MATANIELQS AAEHEAHPTN FIRQIIDEDL ATGKHHNVYT RFPPEPNGYL HIGHAKSICL 

        70         80         90        100        110        120 
NFGIAQDYHG KCNLRFDDTN PVKEDVEYVD SIKQDVEWLG FNWEGEPRYA SDYFDQLYGY 

       130        140        150        160        170        180 
AVELIEKGLA YVDELSPEEM REYRGTLTEA GKNSPYRERS VAENLALFEK MRNGEFAEGK 

       190        200        210        220        230        240 
ACLRAKIDMA SPFMVMRDPV IYRVKFASHH QTGDKWCIYP MYDFTHCISD AIERITHSLC 

       250        260        270        280        290        300 
TLEFQDNRRL YDWVLEHISI ERPLPHQYEF SRLNLEGTLT SKRKLLKLVE EGAVDGWDDP 

       310        320        330        340        350        360 
RMPTISGLRR RGYTPASLRE FCRRIGVTKQ DNVVEFSALE SCIRDDLNIN APRAMAVINP 

       370        380        390        400        410        420 
LKVIIENFET PETLTMPNHP NREEMGTRQV QLTKELYIDQ ADFREEANKQ YKRLVLGKEV 

       430        440        450        460        470        480 
RLRNAYIIKA ERVEKDAEGN IVCVYCSYDP ETLGKNPSDG RKVKGVIQWV SATDCLPAEF 

       490        500        510        520        530        540 
RQYSRLFTMP NPGSEEDIIA AINPQSLVVR QGFVERSVAN ALSEKAYQFE REGYYCADSK 

       550 
DSRPDHLVFN LTVSLKEGF 

« Hide

References

[1]"Complete sequence of Actinobacillus succinogenes 130Z."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Vieille C., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 55618 / 130Z.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000746 Genomic DNA. Translation: ABR74708.1.
RefSeqYP_001344643.1. NC_009655.1.

3D structure databases

ProteinModelPortalA6VP11.
SMRA6VP11. Positions 19-557.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING339671.Asuc_1348.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR74708; ABR74708; Asuc_1348.
GeneID5348033.
KEGGasu:Asuc_1348.
PATRIC20761066. VBIActSuc117883_1410.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0008.
HOGENOMHOG000259232.
KOK01886.
OMAVTHSICT.
OrthoDBEOG6DRPF7.
ProtClustDBPRK05347.

Enzyme and pathway databases

BioCycASUC339671:GHDX-1415-MONOMER.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_ACTSZ
AccessionPrimary (citable) accession number: A6VP11
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: August 21, 2007
Last modified: February 19, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries