UniProtKB - A6VNB3 (SYR_ACTSZ)
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Protein
Arginine--tRNA ligase
Gene
argS
Organism
Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
Status
Functioni
Catalytic activityi
ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation
GO - Molecular functioni
- arginine-tRNA ligase activity Source: UniProtKB-EC
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- arginyl-tRNA aminoacylation Source: InterPro
Keywordsi
Molecular function | Aminoacyl-tRNA synthetase, Ligase |
Biological process | Protein biosynthesis |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | ASUC339671:G1G9D-1161-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)Alternative name(s): Arginyl-tRNA synthetaseUniRule annotation Short name: ArgRSUniRule annotation |
Gene namesi | Name:argSUniRule annotation Ordered Locus Names:Asuc_1094 |
Organismi | Actinobacillus succinogenes (strain ATCC 55618 / 130Z) |
Taxonomic identifieri | 339671 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000071392 | 1 – 575 | Arginine--tRNA ligaseAdd BLAST | 575 |
Interactioni
Subunit structurei
Monomer.UniRule annotation
Protein-protein interaction databases
STRINGi | 339671.Asuc_1094 |
Structurei
3D structure databases
ProteinModelPortali | A6VNB3 |
SMRi | A6VNB3 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 122 – 132 | "HIGH" regionAdd BLAST | 11 |
Sequence similaritiesi
Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation
Phylogenomic databases
eggNOGi | ENOG4105C75 Bacteria COG0018 LUCA |
HOGENOMi | HOG000247212 |
KOi | K01887 |
OMAi | NKPLHLG |
OrthoDBi | POG091H01RF |
Family and domain databases
CDDi | cd00671 ArgRS_core, 1 hit |
Gene3Di | 3.30.1360.701 hit 3.40.50.6201 hit |
HAMAPi | MF_00123 Arg_tRNA_synth, 1 hit |
InterProi | View protein in InterPro IPR001412 aa-tRNA-synth_I_CS IPR001278 Arg-tRNA-ligase IPR005148 Arg-tRNA-synth_N IPR036695 Arg-tRNA-synth_N_sf IPR035684 ArgRS_core IPR008909 DALR_anticod-bd IPR014729 Rossmann-like_a/b/a_fold IPR009080 tRNAsynth_Ia_anticodon-bd |
PANTHERi | PTHR11956 PTHR11956, 1 hit |
Pfami | View protein in Pfam PF03485 Arg_tRNA_synt_N, 1 hit PF05746 DALR_1, 1 hit PF00750 tRNA-synt_1d, 1 hit |
PRINTSi | PR01038 TRNASYNTHARG |
SMARTi | View protein in SMART SM01016 Arg_tRNA_synt_N, 1 hit SM00836 DALR_1, 1 hit |
SUPFAMi | SSF47323 SSF47323, 1 hit SSF55190 SSF55190, 1 hit |
TIGRFAMsi | TIGR00456 argS, 1 hit |
PROSITEi | View protein in PROSITE PS00178 AA_TRNA_LIGASE_I, 1 hit |
i Sequence
Sequence statusi: Complete.
A6VNB3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNIQQLLSEK IRHAMIAAGA QQPAEPAVRQ SGKPQFGDYQ ANGIMGAAKK
60 70 80 90 100
LGLNPREFAQ KVLDNLNLDG IAEKLEIAGP GFINIFLSKN WLVCHADEML
110 120 130 140 150
SAVNFGIKTA KPQTIVVDYS SPNVAKEMHV GHLRSTIIGD AVVRTLEFLG
160 170 180 190 200
NHVIRANHVG DWGTQFGMLI AYLEKMENEN ASAMQLSDLE AFYRAAKEHY
210 220 230 240 250
DNDEAFAEKA RNYVVKLQSG DEYCRIMWKK LVDITMRHNQ ENYDRLNVTL
260 270 280 290 300
TEKDVMGESL YNPMLPEIVA DLKKQGLAVE DDGALVVYLD EFKNKDGDPM
310 320 330 340 350
GVIVQKKDGG YLYTTTDIAA AKYRCHKLHA DRVLVFSDSR QSQHMQQAWL
360 370 380 390 400
ITRKAGYVPD SFSLEHPFFG MMLGKDGKPF KTRTGGTVKL KDLLDEAVER
410 420 430 440 450
ADKLIAERNP DLTAEEKAAV VEAVAIGSVK YSDLSKNRTT DYVFDWDNML
460 470 480 490 500
TFEGNTAPYM QYAYTRIRSI FARAGIEPNS LNDDIVLTDD KERVLVIKLL
510 520 530 540 550
QFEEALNGVA KDGMPHILCQ YLYELAGMFS AFYEACPILN AERPIKNSRL
560 570
KLAALAAKTL KQGLDLLGIK TVEKM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000746 Genomic DNA Translation: ABR74460.1 |
RefSeqi | WP_012072837.1, NC_009655.1 |
Genome annotation databases
EnsemblBacteriai | ABR74460; ABR74460; Asuc_1094 |
KEGGi | asu:Asuc_1094 |
Similar proteinsi
Entry informationi
Entry namei | SYR_ACTSZ | |
Accessioni | A6VNB3Primary (citable) accession number: A6VNB3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 26, 2008 |
Last sequence update: | August 21, 2007 | |
Last modified: | February 28, 2018 | |
This is version 66 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |