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Protein

Chaperone protein HscA homolog

Gene

hscA

Organism
Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein HscA homologUniRule annotation
Gene namesi
Name:hscAUniRule annotation
Ordered Locus Names:Asuc_0868
OrganismiActinobacillus succinogenes (strain ATCC 55618 / 130Z)
Taxonomic identifieri339671 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
Proteomesi
  • UP000001114 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000727281 – 614Chaperone protein HscA homologAdd BLAST614

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi339671.Asuc_0868.

Structurei

3D structure databases

ProteinModelPortaliA6VMP1.
SMRiA6VMP1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C9I. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04044.
OMAiLRGIPAM.
OrthoDBiPOG091H067B.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00679. HscA. 1 hit.
InterProiView protein in InterPro
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
IPR010236. ISC_FeS_clus_asmbl_HscA.
PfamiView protein in Pfam
PF00012. HSP70. 1 hit.
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR01991. HscA. 1 hit.
PROSITEiView protein in PROSITE
PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.

Sequencei

Sequence statusi: Complete.

A6VMP1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLQIAEPG QSAAPHQHKL AIGIDLGTTN SLVATVRNGQ AEILLDEKER
60 70 80 90 100
PLTPSIVHYG DNVTVGYDAG ELASRDPQNT IISVKRLIGR SLNDVQARYP
110 120 130 140 150
NLPYRFVRSE NGLPLLGTAQ GNVSPIEVSG EILKKLTALA QHRLNGELLG
160 170 180 190 200
VVITVPAYFD DAQRQSTKDA AKLAGLNVLR LLNEPTAAAI AYGLDSGREG
210 220 230 240 250
VIAVYDLGGG TFDISILRLS RGVFEVLATG GDTALGGDDF DHLIADWISE
260 270 280 290 300
KSGIQPQDDQ QKRLLIELAA RTKIALTDKP QVSLSYQGWQ GEMQREEFNG
310 320 330 340 350
LISGLVKRSL MACRRALKDA GIGQSEVQEV VMVGGSTRVP FVRDQVGEFF
360 370 380 390 400
QRRPLTSIDP DKVVALGAAI QADILVGNKP DNEMLLLDVI PLSLGIETMG
410 420 430 440 450
GLVEKIIPRN TTIPVARAQE FTTFKDGQTA MSVHVVQGER ELVGDCRSLA
460 470 480 490 500
RFTLRGIPPM AAGAAHIRVT YQVDADGLLS VTAMEKSTGV QSSIQVKPSY
510 520 530 540 550
GLTDDEITQM LKASMENAKE DIGARMLAEQ RVEARRVIEA VLSALLDDQD
560 570 580 590 600
LLNDEELSTV KNALVSLDNL QQGTDTQAIK AGIKALDAAT QEFAARRMDK
610
SIRRALSGQS VDSL
Length:614
Mass (Da):66,225
Last modified:August 21, 2007 - v1
Checksum:i1D4F282B52F2C370
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000746 Genomic DNA. Translation: ABR74238.1.
RefSeqiWP_012072616.1. NC_009655.1.

Genome annotation databases

EnsemblBacteriaiABR74238; ABR74238; Asuc_0868.
KEGGiasu:Asuc_0868.

Similar proteinsi

Entry informationi

Entry nameiHSCA_ACTSZ
AccessioniPrimary (citable) accession number: A6VMP1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: August 21, 2007
Last modified: June 7, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families