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Protein

60 kDa chaperonin

Gene

groL

Organism
Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:Asuc_0662
OrganismiActinobacillus succinogenes (strain ATCC 55618 / 130Z)
Taxonomic identifieri339671 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
Proteomesi
  • UP000001114 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000726281 – 54760 kDa chaperoninAdd BLAST547

Proteomic databases

PRIDEiA6VM38.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi339671.Asuc_0662.

Structurei

3D structure databases

ProteinModelPortaliA6VM38.
SMRiA6VM38.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

A6VM38-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKDVKFGN DARVKMLAGV NVLADAVKVT LGPKGRNVIL DKSFGAPTIT
60 70 80 90 100
KDGVSVAREI ELEDKFENMG AQMVKEVASK ANDAAGDGTT TATVLAQAIV
110 120 130 140 150
NEGLKAVAAG MNPMDLKRGI DKAVAAVVSE LKALSKPCET SKEIEQVGTI
160 170 180 190 200
SANSDSIVGQ LIAQAMEKVG KEGVITVEDG TGLEDELDVV EGMQFDRGYL
210 220 230 240 250
SPYFINKPET ATVEMDNPYI LLVDKKISNI RELLPVLEAV AKAGKPLLII
260 270 280 290 300
AEDVEGEALA TLVVNTMRGI VKVAAVKAPG FGDRRKAMLQ DIAILTAGTV
310 320 330 340 350
ISEEIGMELE KAALEDLGQA KRVVINKDNT TIIDGVGDEA QIKGRVAQIR
360 370 380 390 400
QQIEESTSDY DKEKLQERVA KLAGGVAVIK VGAATEVEMK EKKDRVEDAL
410 420 430 440 450
HATRAAVEEG IVAGGGVALI RAASKAAANL QGDNEEQNVG IKLALRAMEA
460 470 480 490 500
PLRQIVANAG EEASVVASAV KNGEGNYGYN AGTEEYGDMI AMGILDPTKV
510 520 530 540
TRSALQFAAS IAGLMITTEA MVTELPKDDK LDPSAAMGGM GGMGGMM
Length:547
Mass (Da):57,393
Last modified:August 21, 2007 - v1
Checksum:iDF8A88BD03F41740
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000746 Genomic DNA. Translation: ABR74035.1.
RefSeqiWP_012072415.1. NC_009655.1.

Genome annotation databases

EnsemblBacteriaiABR74035; ABR74035; Asuc_0662.
KEGGiasu:Asuc_0662.

Similar proteinsi

Entry informationi

Entry nameiCH60_ACTSZ
AccessioniPrimary (citable) accession number: A6VM38
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: August 21, 2007
Last modified: June 7, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families