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Protein

Xylose isomerase

Gene

xylA

Organism
Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101UniRule annotation1
Active sitei104UniRule annotation1
Metal bindingi232Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 2UniRule annotation1
Metal bindingi271Magnesium 2UniRule annotation1
Metal bindingi296Magnesium 1UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi339Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciASUC339671:G1G9D-521-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Asuc_0500
OrganismiActinobacillus succinogenes (strain ATCC 55618 / 130Z)
Taxonomic identifieri339671 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
Proteomesi
  • UP000001114 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000723811 – 437Xylose isomeraseAdd BLAST437

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi339671.Asuc_0500

Structurei

3D structure databases

ProteinModelPortaliA6VLM8
SMRiA6VLM8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

A6VLM8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNYFDKIEK VNYEGADSIN PFAYKYYNAN EVILGKTMAD HLRLAVCYWH
60 70 80 90 100
TFCWNGNDMF GVGSLDRSWQ KQTDPLAGAK QKADIAFEFL TKLGVPYYCF
110 120 130 140 150
HDVDIAPEGN SYQEYVNNFN TIVDVLEQKQ AETGIKLLWG TANCFTNPRY
160 170 180 190 200
MSGAATNPNP EIFARAGAQV FNAMNATKRL GGENYVLWGG REGYETLLNT
210 220 230 240 250
DLRREREQIG RFMQMVVEHK HKIGFKGTLL IEPKPQEPTK HQYDYDVATV
260 270 280 290 300
YGFLKQFGLE KEIKVNIEAN HATLAGHTFQ HEIATAAALD ILGSIDANRG
310 320 330 340 350
DPQLGWDTDQ FPNSVEENTL AIYEILKAGG LTTGGLNFDA KIRRQSIDPY
360 370 380 390 400
DLFHAHIGAI DVLALSLRRA AKMLEDQTLQ HIVEQRYAGW NGELGQQILN
410 420 430
GKSSLEALAQ AAQHLEPQPV SGQQEYLENL VNSYIYR
Length:437
Mass (Da):49,266
Last modified:August 21, 2007 - v1
Checksum:i5CE3BAF13620395A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000746 Genomic DNA Translation: ABR73875.1
RefSeqiWP_012072255.1, NC_009655.1

Genome annotation databases

EnsemblBacteriaiABR73875; ABR73875; Asuc_0500
KEGGiasu:Asuc_0500

Similar proteinsi

Entry informationi

Entry nameiXYLA_ACTSZ
AccessioniPrimary (citable) accession number: A6VLM8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: August 21, 2007
Last modified: April 25, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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