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A6VLM8

- XYLA_ACTSZ

UniProt

A6VLM8 - XYLA_ACTSZ

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Protein
Xylose isomerase
Gene
xylA, Asuc_0500
Organism
Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011 By similarity
Active sitei104 – 1041 By similarity
Metal bindingi232 – 2321Magnesium 1 By similarity
Metal bindingi268 – 2681Magnesium 1 By similarity
Metal bindingi268 – 2681Magnesium 2 By similarity
Metal bindingi271 – 2711Magnesium 2 By similarity
Metal bindingi296 – 2961Magnesium 1 By similarity
Metal bindingi307 – 3071Magnesium 2 By similarity
Metal bindingi309 – 3091Magnesium 2 By similarity
Metal bindingi339 – 3391Magnesium 1 By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism, Pentose shunt, Xylose metabolism

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciASUC339671:GHDX-518-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomerase (EC:5.3.1.5)
Gene namesi
Name:xylA
Ordered Locus Names:Asuc_0500
OrganismiActinobacillus succinogenes (strain ATCC 55618 / 130Z)
Taxonomic identifieri339671 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
ProteomesiUP000001114: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 437437Xylose isomeraseUniRule annotation
PRO_1000072381Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi339671.Asuc_0500.

Structurei

3D structure databases

ProteinModelPortaliA6VLM8.
SMRiA6VLM8. Positions 2-437.

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.

Phylogenomic databases

eggNOGiCOG2115.
HOGENOMiHOG000252293.
KOiK01805.
OMAiLFHAHIG.
OrthoDBiEOG62NX4R.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6VLM8-1 [UniParc]FASTAAdd to Basket

« Hide

MTNYFDKIEK VNYEGADSIN PFAYKYYNAN EVILGKTMAD HLRLAVCYWH    50
TFCWNGNDMF GVGSLDRSWQ KQTDPLAGAK QKADIAFEFL TKLGVPYYCF 100
HDVDIAPEGN SYQEYVNNFN TIVDVLEQKQ AETGIKLLWG TANCFTNPRY 150
MSGAATNPNP EIFARAGAQV FNAMNATKRL GGENYVLWGG REGYETLLNT 200
DLRREREQIG RFMQMVVEHK HKIGFKGTLL IEPKPQEPTK HQYDYDVATV 250
YGFLKQFGLE KEIKVNIEAN HATLAGHTFQ HEIATAAALD ILGSIDANRG 300
DPQLGWDTDQ FPNSVEENTL AIYEILKAGG LTTGGLNFDA KIRRQSIDPY 350
DLFHAHIGAI DVLALSLRRA AKMLEDQTLQ HIVEQRYAGW NGELGQQILN 400
GKSSLEALAQ AAQHLEPQPV SGQQEYLENL VNSYIYR 437
Length:437
Mass (Da):49,266
Last modified:August 21, 2007 - v1
Checksum:i5CE3BAF13620395A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000746 Genomic DNA. Translation: ABR73875.1.
RefSeqiWP_012072255.1. NC_009655.1.
YP_001343810.1. NC_009655.1.

Genome annotation databases

EnsemblBacteriaiABR73875; ABR73875; Asuc_0500.
GeneIDi5349487.
KEGGiasu:Asuc_0500.
PATRICi20759216. VBIActSuc117883_0532.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000746 Genomic DNA. Translation: ABR73875.1 .
RefSeqi WP_012072255.1. NC_009655.1.
YP_001343810.1. NC_009655.1.

3D structure databases

ProteinModelPortali A6VLM8.
SMRi A6VLM8. Positions 2-437.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 339671.Asuc_0500.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR73875 ; ABR73875 ; Asuc_0500 .
GeneIDi 5349487.
KEGGi asu:Asuc_0500.
PATRICi 20759216. VBIActSuc117883_0532.

Phylogenomic databases

eggNOGi COG2115.
HOGENOMi HOG000252293.
KOi K01805.
OMAi LFHAHIG.
OrthoDBi EOG62NX4R.

Enzyme and pathway databases

BioCyci ASUC339671:GHDX-518-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Actinobacillus succinogenes 130Z."
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Vieille C., Richardson P.
    Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 55618 / 130Z.

Entry informationi

Entry nameiXYLA_ACTSZ
AccessioniPrimary (citable) accession number: A6VLM8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: August 21, 2007
Last modified: September 3, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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