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Protein

Adenylate cyclase

Gene

Asuc_0361

Organism
Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP = 3',5'-cyclic AMP + diphosphate.UniRule annotation

GO - Molecular functioni

  1. adenylate cyclase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

cAMP biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciASUC339671:GHDX-379-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenylate cyclaseUniRule annotation (EC:4.6.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Asuc_0361Imported
OrganismiActinobacillus succinogenes (strain ATCC 55618 / 130Z)Imported
Taxonomic identifieri339671 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
ProteomesiUP000001114: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi339671.Asuc_0361.

Family & Domainsi

Sequence similaritiesi

Belongs to the adenylyl cyclase class-1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3072.
HOGENOMiHOG000270910.
KOiK05851.
OMAiPIHGLFL.
OrthoDBiEOG63JR9H.

Family and domain databases

InterProiIPR000274. Adenylate_cyclase_1.
IPR024686. Adenylate_cyclase_1_CS.
IPR024685. Adenylate_cyclase_1_N.
[Graphical view]
PfamiPF12633. Adenyl_cycl_N. 1 hit.
PF01295. Adenylate_cycl. 1 hit.
[Graphical view]
PIRSFiPIRSF001444. Adenylate_cycl. 1 hit.
PROSITEiPS01092. ADENYLATE_CYCLASE_1_1. 1 hit.
PS01093. ADENYLATE_CYCLASE_1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6VL92-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKYDLEFARK QVADLEKFRL FRALSGTTDE FRYVFQLIAL LLHANHPNLP
60 70 80 90 100
GFVADAPTGI ADFKLTDYQR HYLHEILAQS SDIQFPQIFD RTSYAIDGVY
110 120 130 140 150
VMGSIASIAQ TTSSDLDIWV CLREGLKARE REKLQQKAAA LQRWAKQYEV
160 170 180 190 200
DVNLFLMDQN RFRNFQSSGV MTKENCGSTQ YMLLLDEFYR SAIRLAGKPL
210 220 230 240 250
LWLHLLVEDE KNYESEVDDL IRRGEIDPLE WVDFGGLGKF SANEYFGASL
260 270 280 290 300
WQLYKGIDAP YKAVIKILLL EEYSWEYPNT RLIASDFKFH LLMGHTEDHH
310 320 330 340 350
FDPYLEMLER VTDYLTYRKD FKRLDDMRHC FYLKATEDWW YRNESNWRVD
360 370 380 390 400
LINRLAQDWG WSKETIQDLN LRPFWKIKRV KQSYNKLMQM LMVSYRNLID
410 420 430 440 450
FARKHHVDAN IVPQDISILT RKIYTAFEEL PGKVLLINPQ ISTDLSEPYL
460 470 480 490 500
TFVEVTATDR PVKKGWYMLN QAPEVSGFSH PRYTEYSATL HKLVASAYFN
510 520 530 540 550
GLLMPHTRLH IQSPNVSLPI LQEFITNLAE TLPVHALPPT NDDLHHPCEI
560 570 580 590 600
RQLMVAINLS NDPTKQLTDS KMPIQQSDLF SFGSEQQNLV GSIDFIYRNL
610 620 630 640 650
WNEIRTLHFE GPNAILMALK VLSNKIHHGS TALANIEVYS YSRNYRYSLA
660 670 680 690 700
NIVTALIKKC IDIQLGTNQA ANSQSMLRVA GKNWQFFFEE RGISLHELPE
710 720 730 740 750
NQELPVNELD KELYAEINKN DSVLPVRYEQ NMPEKLQYPS EIDSFASEGF
760 770 780 790 800
LQFFFEDNSD DTFNVYILDE KNHVEIYHRC DGEKEQKINE INYIYTNADS
810 820 830 840
SGNNPYGIIQ QNFNYPQFYR IIHNRYYEGN NPPVHIVPFQ RQAKYT
Length:846
Mass (Da):98,970
Last modified:August 21, 2007 - v1
Checksum:i4FDF0918A9EA7C65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000746 Genomic DNA. Translation: ABR73739.1.
RefSeqiYP_001343674.1. NC_009655.1.

Genome annotation databases

EnsemblBacteriaiABR73739; ABR73739; Asuc_0361.
GeneIDi5348605.
KEGGiasu:Asuc_0361.
PATRICi20758928. VBIActSuc117883_0388.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000746 Genomic DNA. Translation: ABR73739.1.
RefSeqiYP_001343674.1. NC_009655.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi339671.Asuc_0361.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR73739; ABR73739; Asuc_0361.
GeneIDi5348605.
KEGGiasu:Asuc_0361.
PATRICi20758928. VBIActSuc117883_0388.

Phylogenomic databases

eggNOGiCOG3072.
HOGENOMiHOG000270910.
KOiK05851.
OMAiPIHGLFL.
OrthoDBiEOG63JR9H.

Enzyme and pathway databases

BioCyciASUC339671:GHDX-379-MONOMER.

Family and domain databases

InterProiIPR000274. Adenylate_cyclase_1.
IPR024686. Adenylate_cyclase_1_CS.
IPR024685. Adenylate_cyclase_1_N.
[Graphical view]
PfamiPF12633. Adenyl_cycl_N. 1 hit.
PF01295. Adenylate_cycl. 1 hit.
[Graphical view]
PIRSFiPIRSF001444. Adenylate_cycl. 1 hit.
PROSITEiPS01092. ADENYLATE_CYCLASE_1_1. 1 hit.
PS01093. ADENYLATE_CYCLASE_1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production."
    McKinlay J.B., Laivenieks M., Schindler B.D., McKinlay A.A., Siddaramappa S., Challacombe J.F., Lowry S.R., Clum A., Lapidus A.L., Burkhart K.B., Harkins V., Vieille C.
    BMC Genomics 11:680-680(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 55618 / 130ZImported.

Entry informationi

Entry nameiA6VL92_ACTSZ
AccessioniPrimary (citable) accession number: A6VL92
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: January 7, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.