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Protein

Uronate isomerase

Gene

uxaC

Organism
Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:Asuc_0145
OrganismiActinobacillus succinogenes (strain ATCC 55618 / 130Z)
Taxonomic identifieri339671 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
Proteomesi
  • UP000001114 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000727241 – 467Uronate isomeraseAdd BLAST467

Proteomic databases

PRIDEiA6VKM8.

Interactioni

Protein-protein interaction databases

STRINGi339671.Asuc_0145.

Structurei

3D structure databases

ProteinModelPortaliA6VKM8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

A6VKM8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQFMDEDFL LSNDVARTLY FDYAKDQPIF DYHCHLPPKE IAENRLFKDL
60 70 80 90 100
TEIWLAGDHY KWRAMRSAGF DENVITGNAS AYEKYQAWAK TVPLCIGNPI
110 120 130 140 150
YHWTHLELRR PFGITDTLFG PQSADKIWQE CNELLQQPEF SARGIMRRMN
160 170 180 190 200
VKFSGTTDDP IDSLEYHKAI AEDNAFDIEV APSWRPDKAV KIELDQFNDY
210 220 230 240 250
LEQLERVSDT DINSFDALKK ALLKRLEHFD QHGCKSADHG MEIVRFAPIP
260 270 280 290 300
DEKELDRILR LRRSNQALTE LQINQYSTAL LVWLGTEYCK RNWAMQMHIG
310 320 330 340 350
ALRNNNTRMF KLLGADAGFD SIADRTFAEP LSRLLDTMDQ NDELPKTILY
360 370 380 390 400
CLNPRDNEMI ATMIGNFQTG GVAGKIQFGS GWWFNDQKDG MERQLQQLSQ
410 420 430 440 450
LGLLSQFVGM LTDSRSFLSY TRHEYFRRIL CEMVGKWVVN GEAPNDMNLL
460
GNMVKNICYN NAKSYFK
Length:467
Mass (Da):54,150
Last modified:August 21, 2007 - v1
Checksum:i33BCEF1EAD6CB215
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000746 Genomic DNA. Translation: ABR73525.1.
RefSeqiWP_011978801.1. NC_009655.1.

Genome annotation databases

EnsemblBacteriaiABR73525; ABR73525; Asuc_0145.
KEGGiasu:Asuc_0145.
PATRICi20758464. VBIActSuc117883_0162.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000746 Genomic DNA. Translation: ABR73525.1.
RefSeqiWP_011978801.1. NC_009655.1.

3D structure databases

ProteinModelPortaliA6VKM8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi339671.Asuc_0145.

Proteomic databases

PRIDEiA6VKM8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR73525; ABR73525; Asuc_0145.
KEGGiasu:Asuc_0145.
PATRICi20758464. VBIActSuc117883_0162.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_ACTSZ
AccessioniPrimary (citable) accession number: A6VKM8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: August 21, 2007
Last modified: November 2, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.