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A6VJV1 (A6VJV1_METM7) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible oxidation of malate to oxaloacetate By similarity. HAMAP-Rule MF_00487

Catalytic activity

(S)-malate + NAD+ = oxaloacetate + NADH. HAMAP-Rule MF_00487

Sequence similarities

Belongs to the LDH/MDH superfamily. MDH type 3 family. HAMAP-Rule MF_00487

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding7 – 137NAD By similarity HAMAP-Rule MF_00487
Nucleotide binding121 – 1233NAD By similarity HAMAP-Rule MF_00487

Sites

Active site1781Proton acceptor By similarity HAMAP-Rule MF_00487
Binding site861Substrate By similarity HAMAP-Rule MF_00487
Binding site921Substrate By similarity HAMAP-Rule MF_00487
Binding site991NAD By similarity HAMAP-Rule MF_00487
Binding site1231Substrate By similarity HAMAP-Rule MF_00487
Binding site1541Substrate By similarity HAMAP-Rule MF_00487

Sequences

Sequence LengthMass (Da)Tools
A6VJV1 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: F71F3DB39CB0CEE4

FASTA31434,434
        10         20         30         40         50         60 
MEVSIIGASG KIGSVLSLLL AKESYIKNIN LIARNGSINK LKGLKMDLYD AMAAAGQDTN 

        70         80         90        100        110        120 
IQICSDDDLS CTGTSDITIV TAGMARTGDM SRIDLMRENA KIIKNYAKKI ANAGDTKIFM 

       130        140        150        160        170        180 
ISNPVDMMTY KAFIESGYEK NQVFGLGTHL DSMRFKVAVA KYFEVHIDDV RTRIVGEHGD 

       190        200        210        220        230        240 
SMVPLISATA VGGIPIVRLP KYENFPYDRI LEKIKGYGKE IIDLKNGSEY GPASAIVNIV 

       250        260        270        280        290        300 
RCIAHDEKRL LTLSAYIEDE IEGIKGGSCI GVPVKVGKNG IEEVIHMKMN DDEIEGFKKS 

       310 
FDLVKGYCKE IESI 

« Hide

References

[1]"Complete sequence of Methanococcus maripaludis C7."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C7 / ATCC BAA-1331.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000745 Genomic DNA. Translation: ABR66727.1.
RefSeqYP_001330878.1. NC_009637.1.

3D structure databases

ProteinModelPortalA6VJV1.
SMRA6VJV1. Positions 1-314.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING426368.MmarC7_1669.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR66727; ABR66727; MmarC7_1669.
GeneID5328831.
KEGGmmz:MmarC7_1669.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0039.
HOGENOMHOG000213794.
KOK00024.
OMAGANSYEA.
ProtClustDBPRK06223.

Enzyme and pathway databases

BioCycMMAR426368:GHHL-1715-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
HAMAPMF_00487. Malate_dehydrog_3.
InterProIPR001557. L-lactate/malate_DH.
IPR018177. L-lactate_DH_AS.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR011275. Malate_DH_type3.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11540. PTHR11540. 1 hit.
PfamPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
PIRSFPIRSF000102. Lac_mal_DH. 1 hit.
PRINTSPR00086. LLDHDRGNASE.
SUPFAMSSF56327. SSF56327. 1 hit.
PROSITEPS00064. L_LDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA6VJV1_METM7
AccessionPrimary (citable) accession number: A6VJV1
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: February 19, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)