ID   A6VID8_METM7            Unreviewed;       636 AA.
AC   A6VID8;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE            EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN   OrderedLocusNames=MmarC7_1148 {ECO:0000313|EMBL:ABR66214.1};
OS   Methanococcus maripaludis (strain C7 / ATCC BAA-1331).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanococcaceae; Methanococcus.
OX   NCBI_TaxID=426368 {ECO:0000313|EMBL:ABR66214.1};
RN   [1] {ECO:0000313|EMBL:ABR66214.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C7 {ECO:0000313|EMBL:ABR66214.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Anderson I., Sieprawska-Lupa M., Whitman W.B., Richardson P.;
RT   "Complete sequence of Methanococcus maripaludis C7.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000745; ABR66214.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6VID8; -.
DR   STRING; 426368.MmarC7_1148; -.
DR   KEGG; mmz:MmarC7_1148; -.
DR   eggNOG; arCOG04201; Archaea.
DR   HOGENOM; CLU_000022_3_6_2; -.
DR   OrthoDB; 371752at2157; -.
DR   GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR   GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR   CDD; cd05966; ACS; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR011904; Ac_CoA_lig.
DR   InterPro; IPR032387; ACAS_N.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR   PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR   PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR   Pfam; PF16177; ACAS_N; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ABR66214.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          13..66
FT                   /note="Acetyl-coenzyme A synthetase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16177"
FT   DOMAIN          74..460
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          516..596
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   636 AA;  71832 MW;  6BD6DA62E8EEE6B5 CRC64;
     MKTGDKYIML EKYSEMQQKA LDDPEKFWGE QAKCLEWDKT WDKVLDWNPP YAKWFKGGIL
     NASYNCVDRH IKGNRRNKAA IICEKEDGSC GILTYYELYR EINKFANVLE NLGVEKGDVV
     TIYMPMMTEA IIAMLACSRI GAIHNVVFSG FSSDALADRI NDSKSKILVT TNLLYRRGKE
     IDLKKILDKA LLNCNSIKHV VYAKRGSEEF NLVSGKEYFW DELMGGAKSY VEPVPVESEH
     PLFILYTSGT TGSPKGVVHS TGGYLTYATK TMDWTWGLNE MDVFWCTADI GWITGHTYVV
     YGPLSLGATI VLYEGAIDYP EPDRLWGIVE NHGVTLLYTA PTAIRMLMMY GEKWVNTHDL
     STLRLLGSVG EPINPRAWKW YYKVIGKEKC PICDCYWQTE TGGHMIYPAI GLQSVPLKPG
     SATFPGIGID VDVVDNEGNP VDANVKGNLI IKKPWPGMLA GLWNNDERYR AAYWDRFKNK
     FSTSDYAIRD QDGYIWVLGR SDEVLNVSGH RIGTAELEHE LVSNKMVAES AVVGKPDDVK
     GEVPVAFVIL NEKYRELPSN EVKATLIRHI RDTVGPIGTP AMIFFVNKLP KTRSGKIMRR
     ILKKLIMGED IGDVSTLEDN TSLEEVKKEL EDFKYD
//